Marcella La Noce

TL;DR: An overview of the main characteristics and approaches used to identify, isolate, and characterize cancer stem cells from solid tumors is provided.

TL;DR: DPSCs are mesenchymal stem cells that differentiate into different tissues, maintain their characteristics after cryopreservation, differentiate into bone-like tissues when loaded on scaffolds in animal models, and regenerate bone in human grafts and should encourage the development of clinical procedures using DPSCs.

TL;DR: Polydatin may be used as a reliable tool to limit human cancer growth and metastatic spread and a phase II clinical trial shows that it is also well tolerated in humans.

TL;DR: It is concluded that VPA does not induce terminal differentiation of osteoblasts, but stimulates the generation of less mature cells, and specific suppression of an individual HDAC by RNA interference could enhance only a single aspect of osteoblast differentiation, and thus produce selective effects.

TL;DR: The data lead to the assumption that WB samples, fabricated by DPSCs, constitute a noteworthy tool and do not need the use of scaffolds, and therefore they are ready for customized regeneration.