M
Marcelo Franchin
Researcher at State University of Campinas
Publications - 55
Citations - 1703
Marcelo Franchin is an academic researcher from State University of Campinas. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 21, co-authored 44 publications receiving 1203 citations. Previous affiliations of Marcelo Franchin include Universidade Federal de Alfenas & University of São Paulo.
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Journal ArticleDOI
Exploration of avocado by-products as natural sources of bioactive compounds.
Maria Augusta Tremocoldi,Pedro Luiz Rosalen,Marcelo Franchin,Adna Prado Massarioli,Carina Denny,Érica Regina Daiuto,Jonas Augusto Rizzato Paschoal,Priscilla Siqueira Melo,Severino Matias de Alencar +8 more
TL;DR: Agro-industrial by-products of avocado varieties Hass and Fuerte exhibited high radical scavenging activity against synthetic free radicals (DPPH and ABTS) and reactive oxygen species and high ability to reduce Fe3+ to Fe2+.
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Winery by-products: Extraction optimization, phenolic composition and cytotoxic evaluation to act as a new source of scavenging of reactive oxygen species
Priscilla Siqueira Melo,Adna Prado Massarioli,Carina Denny,Luciana Ferracini dos Santos,Marcelo Franchin,Giuliano Elias Pereira,Thais Maria Ferreira de Souza Vieira,Pedro Luiz Rosalen,Severino Matias de Alencar +8 more
TL;DR: These winery by-products can be considered good sources of bioactive compounds, with great potential for application in the food and pharmaceutical industries, and all extracts showed low cytotoxicity against RAW 264.7 cells.
Journal ArticleDOI
Antimicrobial and antiproliferative activities of stingless bee Melipona scutellaris geopropolis
Marcos Guilherme da Cunha,Marcelo Franchin,Livia Camara de Carvalho Galvao,Ana Lúcia Tasca Gois Ruiz,João Carvalho,M. Ikegaki,Severino Matias de Alencar,Hyun Koo,Pedro Luiz Rosalen +8 more
TL;DR: The empirical use of this unique type of geopropolis by folk medicine practitioners was confirmed, since it showed antimicrobial and antiproliferative potential against the cancer cell lines studied.
Journal ArticleDOI
Chemical Characterization and Antioxidant, Antimicrobial, and Anti-Inflammatory Activities of South Brazilian Organic Propolis
Ana Paula Tiveron,Pedro Luiz Rosalen,Marcelo Franchin,Risia Cristina Coelho Lacerda,Bruno Bueno-Silva,Bruna Benso,Carina Denny,Masaharu Ikegaki,Severino Matias de Alencar +8 more
TL;DR: South Brazilian organic propolis can be considered an excellent source of bioactive compounds with great potential of application in the pharmaceutical and food industry.
Journal ArticleDOI
Neutrophil extracellular traps (NETs) exacerbate severity of infant sepsis
David F. Colón,Carlos W. S. Wanderley,Marcelo Franchin,Camila Magalhães Silva,Carlos Hiroji Hiroki,Fernanda V. S. Castanheira,Paula B. Donate,Alexandre H. Lopes,Leila Costa Volpon,Silvia K. Kavaguti,Vanessa F. Borges,Cesar A. Speck-Hernandez,Fernando Silva Ramalho,Ana Paula de Carvalho Panzeri Carlotti,Fabio Carmona,José C. Alves-Filho,Foo Y. Liew,Foo Y. Liew,Fernando Q. Cunha +18 more
TL;DR: This study reveals a hitherto unrecognized mechanism of pediatric sepsis susceptibility and suggests that NETs represents a potential target to improve clinical outcomes of sepsi.