Showing papers by "Marcia Ortiz Mayo Marques published in 2012"
TL;DR: The results suggest that the oil from Citrus aurantium effectively heals gastric ulcers in middle-aged animals; however, safe use of OEC demands special care and precautions.
Abstract: The elderly population has experienced increased life expectancy as well as the increased incidence of gastric ulcers. The peels of fruits from Citrus aurantium L., popularly known in Brazil as orange bitter, are commonly used asatea form for the treatment of gastrointestinal tract disorders, such as ulcer and gastritis. We evaluated the healing effects of essential oil from the peels of Citrus aurantium fruits (OEC) on gastric ulcers in middle-aged rats. We examined the effects of a 14-day chronic OEC treatment on gastric mucosa in middle-aged male Wistar rats that were given acetic-acid-induced gastric lesions by morphometric and immunohistological analyses. Oral OEC treatment significantly reduced the lesion area (76%) within the gastric mucosa and significantly increased (P < .05) the height of regenerated mucosa (59%) when compared to the negative control group. Immunohistochemical analysis of the molecular markers such as COX-2, HSP-70, VEGF, and PCNA in the gastric mucosa confirmed that OEC treatment induced healing effects by increasing the number of new blood vessels and by augmenting gastric mucus in the mucosa glands. These results suggest that the oil from Citrus aurantium effectively heals gastric ulcers in middle-aged animals; however, safe use of OEC demands special care and precautions.
20 citations
TL;DR: In this article, the effect of organic and mineral fertilization on the chemical composition of lemon balm (Melissa officinalis L.) essential oil was evaluated at the "Fazenda Experimental do Gloria" of the Federal University of Uberlândia, and essential oil extraction and GC/MS analyses were completed by the Centre for Research and Development on Plant Genetic Resources of the Campinas Agronomic Institute.
Abstract: Melissa officinalis L., Lamiaceae, is an herb with great growth prospects in the cosmetic industry due to its essential oil. In order to improve its production, it is necessary to study related agricultural practices. This study evaluated the effect of organic and mineral fertilization on the chemical composition of lemon balm (Melissa officinalis L.) essential oil. The assay was conducted at the "Fazenda Experimental do Gloria" of the Federal University of Uberlândia, and essential oil extraction and GC/MS analyses were completed by the Centre for Research and Development on Plant Genetic Resources of the Campinas Agronomic Institute. The assay was conducted in a randomized complete block design with three replications. The tested treatments were six types of fertilization (0, 1, 2, 4, 8 kg.m-2 of cattle manure and mineral fertilizing with 60 g.m-2 of NPK 4-14-8 + 4 g.m-2 of boric acid) with four replications. The essential oil was extracted by hydrodistillation in a modified Clevenger apparatus. The chemical composition was analyzed by GC/MS. The essential oil presented the same compounds for all treatments; however, the relative proportion of some chemical constituents was altered according to the treatment. Neral, geranial, and citronellal were the major constituents.
19 citations
TL;DR: Department of Chemistry and Biochemistry Institute of Biosciences Universidade Estadual Paulista, UNESP, CP 510, CEP 18.618-000, Botucatu, Sao Paulo.
Abstract: Department of Chemistry and Biochemistry Institute of Biosciences Universidade Estadual Paulista, UNESP, CP 510, CEP 18.618-000, Botucatu, Sao Paulo
17 citations