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Showing papers by "Marcia Russell published in 2008"


Journal ArticleDOI
TL;DR: By individual metabolic abnormality, drinking in excess of the dietary guidelines was associated with an increased risk of impaired fasting glucose/diabetes mellitus, hypertriglyceridemia, abdominal Obesity, abdominal obesity, and high blood pressure.
Abstract: Context and Objective: Protective and detrimental associations have been reported between alcohol consumption and the metabolic syndrome. This may be due to variations in drinking patterns and different alcohol effects on the metabolic syndrome components. This study is designed to examine the relationship between alcohol consumption patterns and the metabolic syndrome. Design, Setting, Participants, and Measures: The 1999–2002 National Health and Nutrition Examination Survey is a population-based survey of noninstitutionalized U.S. adults. Current drinkers aged 20–84 yr without cardiovascular disease who had complete data on the metabolic syndrome and drinking patterns were included in the analysis (n = 1529). The metabolic abnormalities comprising the metabolic syndrome included having three of the following: impaired fasting glucose/diabetes mellitus, high triglycerides, abdominal obesity, high blood pressure, and low high-density-lipoprotein cholesterol. Measures of alcohol consumption included usual ...

140 citations


Journal ArticleDOI
TL;DR: Early initiation of alcohol drinking and heavy drinking in adolescence and early adulthood may be associated with an adverse cardiometabolic profile.
Abstract: Context and Objective: Alcohol intakes may vary considerably over a drinker’s lifetime. This study was designed to examine whether lifetime drinking trajectories are associated with cardiovascular risk factors that are used to define the metabolic syndrome (MetS). Design, Setting, Participants, and Outcomes: This is a population-based cross-sectional study. Participants were ever-regular drinkers (n = 2818) selected from healthy controls for the Western New York Health Study (1996–2001) in which lifetime lifestyle was ascertained retrospectively. Prevalence of the MetS and its individual components, including obesity, high triglycerides, low high-density lipoprotein cholesterol, elevated blood pressure, and high fasting glucose, were the main outcomes. Results: Trajectory analyses were based on estimates of total kilograms of ethanol for each age decade between 10 and 59 yr. Two groups of drinkers with distinct lifetime drinking trajectories were obtained, an early peak and a stable trajectory group. Comp...

59 citations


Journal ArticleDOI
TL;DR: An extensive review of the literature is reported in the attempt to answer the pending question on whether or not patients and the general public should be advised to drink moderate amounts of alcohol on the basis of the existing evidence of beneficial effects on total mortality and cardiovascular disease.
Abstract: To the Editor: In a recently published article in Circulation ,1 Drs Kloner and Rezkalla reported an extensive review of the literature in the attempt to answer the pending question on whether or not patients and the general public should be advised to drink moderate amounts of alcohol on the basis of the existing evidence of beneficial effects on total mortality and cardiovascular disease. This is a question of considerable clinical and public health significance that is still waiting for a definitive answer. Although we appreciate the efforts made by the authors1 in their scrutiny of the literature, we …

1 citations