M
Margarete Niebuhr
Researcher at Hannover Medical School
Publications - 31
Citations - 1551
Margarete Niebuhr is an academic researcher from Hannover Medical School. The author has contributed to research in topics: Atopic dermatitis & Cytokine secretion. The author has an hindex of 23, co-authored 31 publications receiving 1381 citations.
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Journal ArticleDOI
Exacerbation of atopic dermatitis on grass pollen exposure in an environmental challenge chamber.
Thomas Werfel,Annice Heratizadeh,Margarete Niebuhr,Alexander Kapp,Lennart M. Roesner,Annika Karch,Veit J. Erpenbeck,Christian Lösche,Thomas Jung,Norbert Krug,Philipp Badorrek,Jens M. Hohlfeld +11 more
TL;DR: In this paper, the severity of AD was assessed at each study visit up to 5 days after challenge by (objective) scoring of AD (SCORAD) and skin areas were each scored using local SCORAD scoring and investigator global assessments.
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Interleukin (IL)-31 induces pro-inflammatory cytokines in human monocytes and macrophages following stimulation with staphylococcal exotoxins.
TL;DR: Interleukin (IL)‐31 induces pro‐inflammatory cytokines in human monocytes and macrophages following stimulation with staphylococcal exotoxins following stimulationWith respect to cytokines, IL-31 acts as a ‘spatially aggregating force’ to reprogram cells to secrete IL-12.
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Staphylococcal exotoxins are strong inducers of IL-22: A potential role in atopic dermatitis
TL;DR: Increased IL-22 secretion induced by staphylococcal exotoxins in the skin partially explains how skin colonization and infection with S aureus can contribute to chronic skin inflammation in AD.
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Functional effects of interleukin 31 in human primary keratinocytes
TL;DR: Functional effects of Interleukin 31 in human primary keratinocytes are studied in order to better understand the role of “self-consistency” in keratinocyte reprograming.
Journal ArticleDOI
Malassezia sympodialis thioredoxin–specific T cells are highly cross-reactive to human thioredoxin in atopic dermatitis
Hari Balaji,Annice Heratizadeh,Katja Wichmann,Margarete Niebuhr,Reto Crameri,Annika Scheynius,Thomas Werfel +6 more
TL;DR: In patients with AD sensitized to Malassezia species, cross-reactivity at the T-cell level to Mala s 13 and the homologous hTrx is detectable and might be relevant for cutaneous inflammation in patients withAD.