M
Mariela C. Humphrey
Researcher at Fred Hutchinson Cancer Research Center
Publications - 3
Citations - 453
Mariela C. Humphrey is an academic researcher from Fred Hutchinson Cancer Research Center. The author has contributed to research in topics: Genotype & Odds ratio. The author has an hindex of 3, co-authored 3 publications receiving 417 citations.
Papers
More filters
Journal ArticleDOI
Prevalence and Predictors of BRCA1 and BRCA2 Mutations in a Population-Based Study of Breast Cancer in White and Black American Women Ages 35 to 64 Years
Kathleen E. Malone,Janet R. Daling,David R. Doody,Li Hsu,Leslie Bernstein,Ralph J. Coates,Polly A. Marchbanks,Michael S. Simon,Jill A. McDonald,Sandra A. Norman,Brian L. Strom,Ronald T. Burkman,Giske Ursin,Dennis Deapen,Linda K. Weiss,Suzanne G. Folger,Jennifer Madeoy,Jennifer Madeoy,Danielle M. Friedrichsen,Nicola M. Suter,Mariela C. Humphrey,Robert Spirtas,Elaine A. Ostrander,Elaine A. Ostrander +23 more
TL;DR: First-time prevalence estimates for BRCA1/BRCA2 in breast cancer cases among understudied racial and age groups are provided and key predictors of mutation carrier status for both White and Black women and women of a wide age spectrum with breast cancer in the general population are shown.
Journal ArticleDOI
Vitamin D receptor polymorphisms and breast cancer risk in a large population-based case-control study of Caucasian and African-American women.
Britton Trabert,Britton Trabert,Kathleen E. Malone,Kathleen E. Malone,Janet R. Daling,Janet R. Daling,David R. Doody,Leslie Bernstein,Giske Ursin,Giske Ursin,Polly A. Marchbanks,Brian L. Strom,Mariela C. Humphrey,Elaine A. Ostrander,Elaine A. Ostrander +14 more
TL;DR: The results provide additional support for an increased risk for breast cancer in postmenopausal Caucasian women with the BsmI bb genotype and shed light on possible differential effects by menopausal status and race.
Journal ArticleDOI
IGF-I and IGFBP-3 polymorphisms and risk of prostate cancer
Danielle M. Friedrichsen,Sarah Hawley,Jainfen Shu,Mariela C. Humphrey,Leah P. Sabacan,Lori Iwasaki,Ruth Etzioni,Elaine A. Ostrander,Janet L. Stanford,Janet L. Stanford +9 more
TL;DR: Several polymorphisms within the IGF‐I and IGFBP‐3 coding regions have been associated with increased serum protein levels, and multiple studies suggest that higher IGF-I and/or lower IGFBP-3 serum levels are positively associated with prostate cancer risk.