M
Marja J. VanWijk
Researcher at University of Amsterdam
Publications - 6
Citations - 1127
Marja J. VanWijk is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Preeclampsia & Pregnancy. The author has an hindex of 6, co-authored 6 publications receiving 1085 citations.
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Journal ArticleDOI
Microparticles in cardiovascular diseases
TL;DR: Although hard evidence for a role of microparticles in cardiovascular diseases at present is still only limited, new evidence is accumulating rapidly to support this theory and new intervention strategies for prevention and treatment of cardiovascular diseases are being developed.
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Vascular function in preeclampsia
TL;DR: In this article, a review attempts to unravel the mechanisms that may contribute to preeclampsia-associated changes in vascular function and to indicate the research needed to improve our understanding of this disease.
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Microparticle subpopulations are increased in preeclampsia: possible involvement in vascular dysfunction?
Marja J. VanWijk,Rienk Nieuwland,Kees Boer,Joris A. M. van der Post,Ed VanBavel,Augueste Sturk +5 more
TL;DR: Numbers of T-cell and granulocyte microparticles are increased in preeclampsia, whether these altered microparticle numbers cause vascular dysfunction in preeClampsia or are a consequence of the disease remains to be established.
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Isolated microparticles, but not whole plasma, from women with preeclampsia impair endothelium-dependent relaxation in isolated myometrial arteries from healthy pregnant women.
TL;DR: Preeclampticmicroparticles, but not healthy pregnant microparticles cause endothelial dysfunction in isolated myometrial arteries from healthy pregnant women after overnight incubation, whereas other preeclamaptic plasma constituents protect the endothelium from this effect.
Journal ArticleDOI
Enhanced coagulation activation in preeclampsia: the role of APC resistance, microparticles and other plasma constituents
Marja J. VanWijk,Kees Boer,R.J. Berckmans,Joost C. M. Meijers,Joris A. M. van der Post,Augueste Sturk,Ed VanBavel,Rienk Nieuwland +7 more
TL;DR: In this paper, the authors investigated whether increased thrombin generation by the plasma itself or its cell-derived microparticles results from increased coagulation activation in pregnancy and further increased in preeclampsia.