M
Mark Schena
Researcher at Stanford University
Publications - 15
Citations - 16322
Mark Schena is an academic researcher from Stanford University. The author has contributed to research in topics: DNA microarray & Gene expression. The author has an hindex of 14, co-authored 15 publications receiving 16088 citations.
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Journal ArticleDOI
Quantitative monitoring of gene expression patterns with a complementary DNA microarray.
TL;DR: A high-capacity system was developed to monitor the expression of many genes in parallel by means of simultaneous, two-color fluorescence hybridization, which enabled detection of rare transcripts in probe mixtures derived from 2 micrograms of total cellular messenger RNA.
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Parallel human genome analysis: microarray-based expression monitoring of 1000 genes
TL;DR: The identification of known and novel heat shock and phorbol ester-regulated genes in human T cells demonstrates the sensitivity of the assay.
Journal ArticleDOI
Discovery and analysis of inflammatory disease-related genes using cDNA microarrays
Renu A. Heller,Mark Schena,Andrew Chai,Dari Shalon,Tod Bedilion,James Gilmore,David E. Woolley,Ronald W. Davis +7 more
TL;DR: The use of the cDNA microarray system as a general approach for dissecting human diseases successfully demonstrates the use of this technology to profile complex diseases and discover novel disease-related genes.
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Microarrays: biotechnology's discovery platform for functional genomics
TL;DR: Advances in microarray technology enable massive parallel mining of biological data, with biological chips providing hybridization-based expression monitoring, polymorphism detection and genotyping on a genomic scale.
Journal ArticleDOI
Identification of the SAAT Gene Involved in Strawberry Flavor Biogenesis by Use of DNA Microarrays
Asaph Aharoni,Leopold C. P. Keizer,Harro J. Bouwmeester,Zhongkui Sun,Mayte Alvarez-Huerta,Harrie A. Verhoeven,Jan Blaas,Adèle van Houwelingen,Ric C. H. de Vos,Hilko van der Voet,Ritsert C. Jansen,Monique Guis,Jos Mol,Ronald W. Davis,Mark Schena,Arjen J. van Tunen,Ann P. O’Connell +16 more
TL;DR: A strawberry alcohol acyltransferase (SAAT) was identified in this paper, which plays a crucial role in flavor biogenesis in ripening fruit, using DNA microarrays and appropriate statistical analyses to dissect a complex developmental process.