Martin Babor

TL;DR: This work shows that dynamical diffraction effects are strong enough to permit unambiguous determination of the absolute structure of material composed of light scatterers and presents a complete structure analysis of a pharmaceutical cocrystal of sofosbuvir and l-proline.

TL;DR: In this article, a new approach is introduced for the comparison of molecular packing and the identification of identical crystal structure motifs, using a simple formula involving the distances between molecular centres and the relative orientations of molecular entities inside a finite molecular cluster.

TL;DR: In this article, the authors performed a tailor-made systematic solvate screening and tested several solution and slurry based methods in the solvates screening for their suitability and success rate.

TL;DR: Search for new multicomponent solid forms has become a key step in the pharmaceutical drug development and Apremilast, a poorly soluble API used for the treatment of psoriatic arthritis, was used as a template for this study.

TL;DR: A new co-crystal of pharmaceutical active ingredient Apremilast with benzoic acid significantly improves key properties like the dissolution and stability of an otherwise poorly soluble Ap Remilast and is proposed to be combined into a single methodology based on solubility data.