Mary E. McCaul

TL;DR: The robust dopamine release in men could account for increased vulnerability to stimulant use disorders and methamphetamine toxicity and may have implications for the interpretation of sex differences in other illnesses involving the striatum.

TL;DR: Evidence is provided of interrelationships between glucocorticoid levels, subjective responses to IV AMPH, and brain DA release in humans, suggesting that individual differences in HPA axis function may influence vulnerability to alcohol and drug dependence in humans.

TL;DR: This preliminary study was designed to test the hypothesis that the Asn40Asp substitution polymorphism in the mu-opioid receptor influences HPA axis activation induced by opioid receptor blockade and found that subjects expressing the variant polymorphism had lower scores on the Conscientiousness Factor and associated subscales of NEO Personality Inventory.

TL;DR: Type of substance abuse may be overemphasized as a predictor of outpatient drug-free treatment retention, and that greater emphasis should be placed on tailoring treatment to patients' cultural, gender and vocational needs.

TL;DR: Analysis of the largest sample size to date and widely used Trier Social Stress Test data confirm that men show more robust activation of the HPA axis response to the TSST than do women in the follicular phase of the menstrual cycle, and testosterone results suggest an inhibitory effect on Hpa axis reactivity in men.