M
Masahiro Kashiwaba
Researcher at Harvard University
Publications - 12
Citations - 1397
Masahiro Kashiwaba is an academic researcher from Harvard University. The author has contributed to research in topics: Internal medicine & Breast cancer. The author has an hindex of 5, co-authored 5 publications receiving 1356 citations.
Papers
More filters
Journal ArticleDOI
Induction of antitumor activity by immunization with fusions of dendritic and carcinoma cells.
TL;DR: The results show that the fusion cells stimulate naive T cells in the primary mixed lymphocyte reaction (MLR) and induce MC38 tumor-specific CTLs in vivo and induces rejection of established metastases.
Journal ArticleDOI
Reversal of tolerance to human MUC1 antigen in MUC1 transgenic mice immunized with fusions of dendritic and carcinoma cells
Jianlin Gong,Dongshu Chen,Masahiro Kashiwaba,Yongqing Li,Ling Chen,Hideya Takeuchi,Hui Qu,Gerald J. Rowse,Sandra J. Gendler,Donald Kufe +9 more
TL;DR: It is demonstrated that unresponsiveness to the M UC1 tumor-associated antigen is reversible by immunization with heterokaryons of dendritic cells and MUC1-positive carcinoma cells.
Journal ArticleDOI
Induction of Antitumor Immunity by Vaccination of Dendritic Cells Transfected with MUC1 RNA
TL;DR: It is demonstrated that vaccination of DC transfected with M UC1 RNA and IL-12 reverses tolerance to MUC1 and induces immunity against MUC 1-positive tumors.
Journal ArticleDOI
Activation of antitumor cytotoxic T lymphocytes by fusions of human dendritic cells and breast carcinoma cells
TL;DR: The results show that autologous T cells are primed by the fusion cells to induce MHC class I-dependent lysis of autOLOGous breast tumor cells.
Journal ArticleDOI
Induction of antigen-specific antitumor immunity with adenovirus-transduced dendritic cells.
Jianlin Gong,Ling Chen,Dongshu Chen,Masahiro Kashiwaba,Yoshinobu Manome,Toshihide Tanaka,Donald Kufe +6 more
TL;DR: The results demonstrate adenovirus (Ad)-mediated transduction of the β-galactosidase gene in mouse DC and support the usefulness of Ad-transduced DC for in vivo immunization against tumor-associated antigens.