M
Masako Kimura
Researcher at Kanazawa University
Publications - 7
Citations - 79
Masako Kimura is an academic researcher from Kanazawa University. The author has contributed to research in topics: Blood proteins & Gliclazide. The author has an hindex of 3, co-authored 7 publications receiving 76 citations.
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Journal ArticleDOI
Influence of blood proteins on biomedical analysis. III. Pharmacokinetics and protein binding of gliclazide.
TL;DR: Gliclazide predominantly binds with albumin in the blood and its binding ratio is not constant, but variable according to the dose-relation between the drug and the serum protein.
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Head-space gas-chromatographic determination of 3-hydroxybutyrate in plasma after enzymic reactions, and the relationship among the three ketone bodies.
TL;DR: In this article, a reproducible method for determination of D-3-hydroxybutyrate (3-OHB) in plasma, it is converted to acetone by use of 3-hydrox butyrate dehydrogenase (EC 1.1.30) coupled with acetoacetate decarboxylase, and the resulting acetone is detected by headspace gas chromatography.
Journal ArticleDOI
Reversed-Phase High-Performance Liquid Chromatographic Determination of Gliclazide in Human Plasma
Masako Kimura,Kunio Kobayashi,Mitsuo Hata,Akira Matsuoka,Shigeo Kaneko,Hisami Kitamura,Yukio Kimura +6 more
TL;DR: The decay curve of plasma gliclazide in a diabetic patient given 80 mg of the drug orally was determined by the present method and GLC (ECD method), and the two results agreed well.
Journal ArticleDOI
Influence of Blood Proteins on Biomedical Analysis. VII. Electrophoretic Analysis of the Interaction of Pseudocholinesterase with Fatty Acid and/or Human Serum Albumin
Takafumi Sakoguchi,Kunio Kobayashi,Masako Kimura,Ayumi Hase,Mitsuko Shimozawa,Akira Matsuoka +5 more
TL;DR: It was demonstrated that pchE binds with n-[1-14C] lauric acid, suggesting that the FA-induced inhibition of p chE activity is based on the interaction of the enzyme with FA.
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Influence of blood proteins on biomedical analysis. VI. Effect of bovine serum albumin on the color reaction of xanthurenic acid with 4-aminoantipyrine--inhibition of antipyrine red production by bovine serum albumin.
Takafumi Sakoguchi,Kunio Kobayashi,Masako Kimura,Ayumi Hase,Mitsuko Shimozawa,Akira Matsuoka +5 more