A review of the biological response to ionic dissolution products from bioactive glasses and glass-ceramics

Context.— Aspirin has been widely used to prevent myocardial infarction and ischemic stroke but some studies have suggested it increases risk of hemorrhagic stroke. Objective.— To estimate the risk of hemorrhagic stroke associated with aspirin treatment. Data Sources.— Studies were retrieved using MEDLINE (search terms, aspirin, cerebrovascular disorders, and stroke), bibliographies of the articles retrieved, and the authors’ reference files. Study Selection.— All trials published in English-language journals before July 1997 in which participants were randomized to aspirin or a control treatment for at least 1 month and in which the incidence of stroke subtype was reported. Data Extraction.— Information on country of origin, sample size, duration, study design, aspirin dosage, participant characteristics, and outcomes was abstracted independently by 2 authors who used a standardized protocol. Data Synthesis.— Data from 16 trials with 55 462 participants and 108 hemorrhagic stroke cases were analyzed. The mean dosage of aspirin was 273 mg/d and mean duration of treatment was 37 months. Aspirin use was associated with an absolute risk reduction in myocardial infarction of 137 events per 10 000 persons (95% confidence interval [CI], 107-167;P,.001) and in ischemic stroke, a reduction of 39 events per 10 000 persons (95% CI, 17-61; P,.001). However, aspirin treatment was also associated with an absolute risk increase in hemorrhagic stroke of 12 events per 10 000 persons (95% CI, 5-20; P,.001). This risk did not differ by participant or study design characteristics. Conclusions.— These results indicate that aspirin therapy increases the risk of hemorrhagic stroke. However, the overall benefit of aspirin use on myocardial infarction and ischemic stroke may outweigh its adverse effects on risk of hemorrhagic stroke in most populations.

A Meta-analysis of Randomized Controlled Trials

Gait Analysis. An Introduction

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Basic Biomechanics of the Musculoskeletal System

Deep eutectic solvents for the production and application of new materials

Preparation of mullite-TiB2-CNTs hybrid composite through spark plasma sintering

Co-reinforcing of mullite-TiN-CNT composites with ZrB2 and TiB2 compounds

Effects of ZrB2 reinforcement on microstructure and mechanical properties of a spark plasma sintered mullite-CNT composite

Traditional Iranian Medicine (TIM) or Persian Medicine consists of the sum total of all the knowledge and practices used in diagnosis, prevention and elimination of diseases in Persia from ancient times to present. It is based entirely on practical experience and observations passed down from generation to generation. Traditional medicine has the advantage of being considered as part of the culture therefore, bypassing cultural issues that may affect the practice of medicine. On the other hand, it can be used in conjunction with and as an aid to the conventional medicine. Development and promotion of traditional medicine could be considered as respect and honor to the culture and heritage of the people all around the world.

Masoud Alizadeh

Papers

Preparation of mullite-TiB2-CNTs hybrid composite through spark plasma sintering

Co-reinforcing of mullite-TiN-CNT composites with ZrB2 and TiB2 compounds

Effects of ZrB2 reinforcement on microstructure and mechanical properties of a spark plasma sintered mullite-CNT composite

The Traditional Iranian Medicine Point of View on Health and Disease

Fabrication of magnesium-boron carbide metal matrix composite by powder metallurgy route: Comparison between microwave and spark plasma sintering