M
Maureen Owen
Researcher at University of Oxford
Publications - 5
Citations - 3565
Maureen Owen is an academic researcher from University of Oxford. The author has contributed to research in topics: Stromal cell & Cell culture. The author has an hindex of 5, co-authored 5 publications receiving 3455 citations.
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Book ChapterDOI
Stromal Stem Cells: Marrow‐Derived Osteogenic Precursors
Maureen Owen,A. J. Friedenstein +1 more
TL;DR: In vivo and in vitro studies have shown that CFU-F are a heterogeneous population of stem and progenitor cells and that their differentiation in vitro can be modified at the colony level, which supports the hypothesis that there are stromal stem cells present in the soft connective tissues associated with marrow and bone surfaces.
Journal ArticleDOI
Evidence for an inverse relationship between the differentiation of adipocytic and osteogenic cells in rat marrow stromal cell cultures
TL;DR: In this paper, the differentiation of adipocytic and osteogenic cells was investigated in cultures of adult rat marrow stromal cells using morphological criteria, changes in expression of procollagen mRNAs, consistent with a switch from the synthesis of predominantly fibrillar (types I and III) to basement membrane (type IV) collagen, and the induction of expression of aP2, a specific marker for differentiation.
Journal ArticleDOI
Marrow stromal stem cells.
TL;DR: Evidence for the hypothesis that there areStromal stem cells present in the soft connective tissues associated with marrow and bone surfaces that are able to give rise to a number of different cell lines is reviewed and the possibility that the marrow stromal system is part of a wider stromAL cell system of the body is proposed.
Journal ArticleDOI
Evidence for an inverse relationship between the differentiation of adipocytic and osteogenic cells
TL;DR: The results demonstrate an inverse relationship between the differentiation of adipocytic and osteogenic cells in this culture system and are consistent with the possibility that the regulation of adipogenesis and osteogenesis can occur at the level of a common precursor in vivo.
Journal ArticleDOI
The D-D cross-section and angular distribution between 55 and 430 keV
TL;DR: In this article, the cross-section and angular distribution of protons from the D-D reaction using thin gas targets have been measured from 55 to 430 keV and the results have been expressed in the form