M
Mengcheng Jiang
Researcher at Peking University
Publications - 12
Citations - 203
Mengcheng Jiang is an academic researcher from Peking University. The author has contributed to research in topics: Computer science & Digital polymerase chain reaction. The author has an hindex of 4, co-authored 8 publications receiving 132 citations.
Papers
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Journal ArticleDOI
Centrifugal micro-channel array droplet generation for highly parallel digital PCR
TL;DR: A novel technology to produce monodisperse emulsion droplets with high efficiency and high throughput using a bench-top centrifuge, and demonstrates that this cost-effective method not only eliminates the usage of complex microfluidic devices and control systems, but also greatly suppresses the loss of materials and cross-contamination.
Journal ArticleDOI
High-throughput single-cell whole-genome amplification through centrifugal emulsification and eMDA.
Yusi Fu,Fangli Zhang,Xiannian Zhang,Junlong Yin,Meijie Du,Mengcheng Jiang,Lu Liu,Jie Li,Yanyi Huang,Jianbin Wang +9 more
TL;DR: MiCA-eMDA increases the single-run throughput of scWGA to a few dozen, and enables the assessment of copy number variations and alterations at 50-kb resolution, and downstream target enrichment further enables the detection of SNVs with 20% allele drop-out.
Journal ArticleDOI
Three-dimensional digital PCR through light-sheet imaging of optically cleared emulsion.
Peiyu Liao,Mengcheng Jiang,Zitian Chen,Fangli Zhang,Yue Sun,Jun Nie,Meijie Du,Jianbin Wang,Peng Fei,Yanyi Huang +9 more
TL;DR: The CLEAR-dPCR introduced herein solves the two problems by integrating optically cleared monodisperse droplet generation and light-sheet fluorescence microscopy and fulfills a genuinely lossless and contamination-free digital PCR approach.
Journal ArticleDOI
Reconstruction of Dynamic and Reversible Color Change using Reflectin Protein.
TL;DR: The in vitro reconstruction system presented here may serve as an initial step for designing bio-inspired optical materials based on reflectin protein and suggest a possible role of reflectin in color dynamics.
Journal ArticleDOI
Rotational scan digital LAMP for accurate quantitation of nucleic acids
Mengcheng Jiang,Peiyu Liao,Yue Sun,Xinyang Shao,Zitian Chen,Peng Fei,Jianbin Wang,Yanyi Huang +7 more
TL;DR: In this article, rotational scan digital loop-mediated amplification (RS-dLAMP) is proposed to obtain digital signals from multiple droplets generated by centrifugation and self-tile by gravitation into a tubular space between two coaxial cylinders.