M
Michael E. Hadwiger
Researcher at University of Kansas
Publications - 4
Citations - 198
Michael E. Hadwiger is an academic researcher from University of Kansas. The author has contributed to research in topics: Detection limit & Capillary electrophoresis. The author has an hindex of 4, co-authored 4 publications receiving 194 citations.
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Journal ArticleDOI
Optimization of the separation and detection of the enantiomers of isoproterenol in microdialysis samples by cyclodextrin-modified capillary electrophoresis using electrochemical detection.
TL;DR: The detection limits using UV absorbance detection were found to be too high to determine the concentration of isoproterenol in plasma for a sufficient time following administration to establish the pharmacokinetics.
Journal ArticleDOI
Relationship of flavonoid oxidation potential and effect on rat hepatic microsomal metabolism of benzene and phenol
Howard P. Hendrickson,Moshen Sahafayen,Matthew A. Bell,Arlen D. Kaufman,Michael E. Hadwiger,Craig E. Lunte +5 more
TL;DR: The effect of Flavonoids on microsomal phenol hydroxylase activity was found to correlate well with the oxidation potential for flavonoid aglycones and a linear relation was found between the degree of inhibition and the number of sugar residues for glycosylated flavonoids.
Journal ArticleDOI
Simultaneous determination of the elimination profiles of the individual enantiomers of racemic isoproterenol using capillary electrophoresis and microdialysis sampling
TL;DR: It is demonstrated that a difference in the elimination half-lives of the enantiomers of ISP does exist and because each enantiomer was simultaneously determined in each animal a paired two-sample t-Test could also be done.
Journal ArticleDOI
Liquid chromatographic determination of tacrine and its metabolites in rat bile microdialysates.
TL;DR: A microbore liquid chromatographic method using a phenyl stationary phase was developed for the determination of 9-amino-1,2,3,4-tetrahydroacridine (tacrine, THA) and its metabolites in microdialysis samples of bile.