M
Michael E. Pichichero
Researcher at Rochester General Health System
Publications - 134
Citations - 4898
Michael E. Pichichero is an academic researcher from Rochester General Health System. The author has contributed to research in topics: Streptococcus pneumoniae & Otitis. The author has an hindex of 34, co-authored 134 publications receiving 4207 citations. Previous affiliations of Michael E. Pichichero include University of Rochester & National Institutes of Health.
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Journal ArticleDOI
Immune responses in neonates
TL;DR: This review focuses mainly on the developmental and functional mechanisms of the human neonatal immune system and the mechanism of innate and adaptive immunity and the role of neutrophils, antigen presenting cells, differences in subclasses of T lymphocytes (Th1, Th2, Tregs and B cells are discussed.
Journal ArticleDOI
Comparison of 13 Acellular Pertussis Vaccines: Overview and Serologic Response
Kathryn M. Edwards,Bruce D. Meade,Michael D. Decker,George F. Reed,Margaret B. Rennels,Mark C. Steinhoff,Edwin L. Anderson,Janet A. Englund,Michael E. Pichichero,Maria A. Deloria,Adamadia Deforest +10 more
TL;DR: It is clear that DTaP vaccines can stimulate immune responses that exceed those of licensed whole-cell vaccine with respect to the measured antibodies.
Journal ArticleDOI
Maternal immunization with tetanus–diphtheria–pertussis vaccine: effect on maternal and neonatal serum antibody levels
TL;DR: There was a significant increase in the odds that newborns from mothers who received Tdap during pregnancy have antibodies that may provide protection against diphtheria, pertussis toxin, and fimbriae 2/3.
Journal Article
Comparison of 13 Acellular Pertussis Vaccines: Adverse Reactions
Michael D. Decker,Kathryn M. Edwards,Mark C. Steinhoff,Margaret B. Rennels,Michael E. Pichichero,Janet A. Englund,Edwin L. Anderson,Maria A. Deloria,George F. Reed +8 more
TL;DR: The authors compared the reactogenicity of a licensed conventional whole-cell (WCL) and 13 acellular pertussis vaccines that differed in the source, manufacture, and quantity of included antigens; all vaccines included diphtheria and tetanus toxoids.
Journal ArticleDOI
Comparison of 13 Acellular Pertussis Vaccines: Adverse Reactions
Kathryn M. Edwards,Michael D. Decker,Mark C. Steinhoff,Margaret B. Rennels,Michael E. Pichichero,Janet A. Englund,Edwin L. Anderson,Maria A. Deloria,George F. Reed +8 more
TL;DR: Although there were differences among the acellular vaccines, none was consistently the most or least reactogenic; all were associated with substantially fewer and less severe adverse reactions than a standard commercial whole-cell vaccine.