Showing papers by "Michael P. Alexander published in 1983"
TL;DR: Clinical and anatomic data is gathered on four patients with this dysarthria without aphasia, caused by small lesions of the motor system for articulation: pars opercularis, inferior prerolandic gyrus, or white matter deep to those regions.
Abstract: • A syndrome of dysarthria following the appearance of small left frontal-lobe lesions has been recognized for many years but identified by numerous labels Varied terminology has led to confusion in the literature and inadequate recognition of this syndrome as a distinctive clinical entity We gathered clinical and anatomic (computed tomographic) data on four patients with this dysarthric syndrome and reviewed cases from the literature that contained sufficient clinical and anatomic data for comparison These patients had a distinctive syndrome of dysarthria without aphasia, caused by small lesions of the motor system for articulation: pars opercularis, inferior prerolandic gyrus, or white matter deep to those regions This syndrome should be distinguished from Broca's aphasia, Broca's area aphasia, transcortical aphasia, and subcortical aphasia Aphemia is not mild Broca's aphasia; it is severe dysarthria, at times in the setting of transient Broca's aphasia
173 citations
TL;DR: The material, which may be unfamiliar to most readers, is organized in a thoughtful manner, and allows easy progress through the various anatomical, neurochemical, and physiological evidences of nervous system recovery.
Abstract: Most of this book (chapters 4 through 16) is a review of the demonstrated and potential mechanisms of recovery from brain damage, and this review is good. The material, which may be unfamiliar to most readers, is organized in a thoughtful manner. It allows easy progress through the various anatomical, neurochemical, and physiological evidences of nervous system recovery. Animal experiments are reviewed in detail, allowing the reader to make some independent judgment of their validity and value. For each possible aspect of recovery, both the positive and negative data are presented in a fair manner, and there are numerous occasions in the text when the authors stop to summarize and to clarify succinctly an entire area of research. Areas of research that might seem unrelated, such as axonal sprouting and denervation supersensitivity, are tied together in the text in a useful manner. The audience for these chapters should include neurologists,
52 citations