M
Michel Rousseau
Researcher at Ohio State University
Publications - 4
Citations - 176
Michel Rousseau is an academic researcher from Ohio State University. The author has contributed to research in topics: Antibody & Monoclonal antibody. The author has an hindex of 3, co-authored 4 publications receiving 175 citations.
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Journal ArticleDOI
Radioimmunoguided surgery using the monoclonal antibody B72.3 in colorectal tumors
Brenda J. Sickle-Santanello,Patric J. O'Dwyer,Cathy Mojzisik,Steven E. Tuttle,George H. Hinkle,Michel Rousseau,Jeffrey Schlom,David Colcher,Marlin O. Thurston,Carol Nieroda,Armando Sardi,William B. Farrar,John P. Minton,Edward W. Martin +13 more
TL;DR: The authors have developed a hand-held gamma-detecting probe (GDP) for intraoperative use that improves the sensitivity of external radioimmunodetection and may influence the short-term morbidity and mortality of surgery for colorectal cancer.
Journal ArticleDOI
Intraoperative probe-directed immunodetection using a monoclonal antibody.
Patrick J. O'Dwyer,Cathy Mojzisik,George H. Hinkle,Michel Rousseau,John O. Olsen,Steven E. Tuttle,Rolf F. Barth,Marlin O. Thurston,Daniel P. McCabe,William B. Farrar,Edward W. Martin +10 more
TL;DR: Preliminary data demonstrate that probe-directed, intraoperative radioimmunodetection can assist the surgeon in detecting subclinical tumor deposits and thus better evaluate the extent of primary or recurrent colorectal cancers intraoperatively.
Journal ArticleDOI
Localization by hand-held gamma probe of tumor labeled with antibody “cocktail”
Armando Sardi,M. Alam Siddiqi,George H. Hinkle,Michel Rousseau,Mark Gersman,Tim Hill,John O. Olsen,Steven E. Tuttle,Donn C. Young,David Houchens,Marlin O. Thurston,Edward W. Martin +11 more
TL;DR: Five groups of congenitally athymic female nude mice bearing subcutaneous implants of CX-1 and/or SW-1116 tumor in the hind limbs received iodine-125 radio-labeled monoclonal antibodies (MoAbs) B72.3, 17-1A, and cocktail to enhance targeting of some tumor sites.
Journal ArticleDOI
An Assessment of Prolonged Reactivity of Seven Monoclonal Antibodies Against CX-1 Tumor Xenografts Using A Hand-Held Gamma-Detecting Probe
Carol Nieroda,M. Alam Siddiqi,George H. Hinkle,Tim Hill,Cathy Mojzisik,John O. Olsen,Michel Rousseau,Mark Gersman,David Houchens,Armando Sardi,Jeff Schlom,Jean Simpson,Donn C. Young,Marlin O. Thurston,Edward W. Martin +14 more
TL;DR: Data indicate progressive clearance of the antibodies from the background tissue and a persistence of labeled MAb activity in tumor resulting in improved tumor localization with increasing postinjection time.