M
Michele D'Amico
Researcher at Seconda Università degli Studi di Napoli
Publications - 196
Citations - 5101
Michele D'Amico is an academic researcher from Seconda Università degli Studi di Napoli. The author has contributed to research in topics: Receptor & Inflammation. The author has an hindex of 33, co-authored 195 publications receiving 4430 citations. Previous affiliations of Michele D'Amico include Royal Free Hospital & Queen Mary University of London.
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Journal ArticleDOI
Eculizumab treatment in patients with COVID-19: preliminary results from real life ASL Napoli 2 Nord experience.
F Diurno,Fabio Giuliano Numis,Giovanni Porta,F Cirillo,S Maddaluno,Alfonso Ragozzino,P De Negri,C Di Gennaro,Antonio Pagano,Enrico Allegorico,L Bressy,Giorgio Bosso,A. Ferrara,Claudia Serra,A Montisci,Michele D'Amico,S Schiano Lo Morello,G Di Costanzo,A G Tucci,Paolo Marchetti,U Di Vincenzo,I Sorrentino,A Casciotta,Mario Fusco,Carlo Buonerba,Massimiliano Berretta,Manuela Ceccarelli,Giuseppe Nunnari,Y Diessa,S Cicala,Gaetano Facchini +30 more
TL;DR: Preliminary data obtained with anti-complement C5 therapy with eculizumab in COVID-19 patients admitted to intensive care unit (ICU) of ASL Napoli 2 Nord support eculIZumab use as an off-label treatment of CO VID-19, pending confirmation from the ongoing SOLID-C19 trial.
Journal ArticleDOI
Acute Hyperglycemia Induces Nitrotyrosine Formation and Apoptosis in Perfused Heart From Rat
Antonio Ceriello,Lisa Quagliaro,Michele D'Amico,Clara Di Filippo,Raffaele Marfella,Francesco Nappo,Liberato Berrino,Francesco Rossi,Dario Giugliano +8 more
TL;DR: It is demonstrated that high glucose for 2 h is enough to increase iNOS gene expression and NO release in working rat hearts, a condition favoring the production of peroxynitrite.
Journal ArticleDOI
Myocardial infarction in diabetic rats: role of hyperglycaemia on infarct size and early expression of hypoxia-inducible factor 1.
Raffaele Marfella,Michele D'Amico,C Di Filippo,Elena Piegari,Francesco Nappo,Katherine Esposito,Liberato Berrino,Francesca Rossi,Dario Giugliano +8 more
TL;DR: The findings show that myocardial infarct size in the rat is increased in hyperglycaemic conditions and is associated with a reduced expression of the HIF-1α gene, suggesting a state of pseudohypoxia.
Journal ArticleDOI
Circulating microRNA changes in heart failure patients treated with cardiac resynchronization therapy: responders vs. non-responders
Raffaele Marfella,Clara Di Filippo,Nicoletta Potenza,Celestino Sardu,Maria Rosaria Rizzo,Mario Siniscalchi,Emilio Musacchio,Michelangela Barbieri,Ciro Mauro,Nicola Mosca,Francesco Solimene,Maria Teresa Mottola,Aniello Russo,Francesco Rossi,Giuseppe Paolisso,Michele D'Amico +15 more
TL;DR: This work studied whether LV reverse remodelling after CRT was associated with changes of circulating miRNAs in patients with heart failure (HF) and dyssynchrony.
Journal ArticleDOI
Long-term inhibition of dipeptidyl peptidase-4 in Alzheimer's prone mice.
Michele D'Amico,Clara Di Filippo,Raffaele Marfella,Angela Maria Abbatecola,Franca Ferraraccio,Francesco Rossi,Giuseppe Paolisso +6 more
TL;DR: The long-term inhibition of the endogenous DPP-4 enzymes with sitagliptin can significantly delay some forms of AD pathology, including amyloid deposition, when administered early in the disease course of a transgenic mouse model of AD.