M
Miro Brzin
Researcher at University of Ljubljana
Publications - 36
Citations - 715
Miro Brzin is an academic researcher from University of Ljubljana. The author has contributed to research in topics: Acetylcholinesterase & Denervation. The author has an hindex of 15, co-authored 36 publications receiving 710 citations.
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Journal ArticleDOI
Recovery of Acetylcholinesterase in the Diaphragm, Brain, and Plasma of the Rat After Irreversible Inhibition by Soman: A Study of Cytochemical Localization and Molecular Forms of the Enzyme in the Motor End Plate
TL;DR: Recovery of AChE activity in brain recovered in a similar way as in muscle, whereas soluble plasma cholinesterases recovered faster, apparently without a slow initial phase.
Journal ArticleDOI
A comparison of the effect of cholinesterase inhibitors on end-plate current and on cholinesterase activity in frog muscle.
M. Kordas,Miro Brzin,Živa Majcen +2 more
TL;DR: The changes in the end-plate current, observed at a relatively high concentration of reversible inhibitors, are thought to be related either to a presynaptic, or to a postsynaptic “curare-like” action of these drugs.
Journal ArticleDOI
Electron microscopic-cytochemical and biochemical studies of acetylcholinesterase activity in denervated muscle of rabbits.
TL;DR: The increase in levels of AChE activity, the change to predominantly soluble form, and the large numbers of new cytochemically active sites indicate that synthesis of new enzyme has taken place.
Journal ArticleDOI
Cholinesterase in denervated end plates and muscle fibres.
Miro Brzin,Živa Majcen-Tkačev +1 more
TL;DR: The ChE distribution pattern was changed so that the end plate region became less active in the denervated muscle than in the normal one, and the decrease in ChE activity in the end plates seems to be largely compensated for by an increase of this enzyme elsewhere in the muscle.
Journal ArticleDOI
Acetylcholinesterase activity in the myotube and muscle satellite cell of the fetal rabbit an electron microscopic-cytochemical and biochemical study
TL;DR: The following possibilities that are discussed are that soluble AChE may play a role in fusion of myotubes, be involved in widespread sarcolemmal acetylcholine sensitivity and contribute to the junctional enzyme.