A multimedia collaboration system that facilitates more efficient, free-flowing collaboration sessions. The role of the presenter can be exchanged among participants in a collaboration session. The multimedia collaboration system is configured so that control of a collaboration session can be exchanged freely between participants in the collaboration session. The multimedia collaboration system enables participants in the collaboration session to determine the pace and course of the session.

Methods and apparatus for providing egalitarian control in a multimedia collaboration session

The present invention provides peptides having an amino acid sequence that is the amino acid sequence of a human bactericidal/permeability-increasing protein (BPI) functional domain or a subsequence thereof, and variants of the sequence or subsequence thereof, having at least one of the BPI biological activities, such as heparin binding, heparin neutralization, LPS binding, LPS neutralization or bactericidal activity. The invention provides peptides and pharmaceutical compositions of such peptides for a variety of therapeutic uses.

Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof

The present invention provides a crystallized Bactericidal Permeability-Increasing (BPI) protein; methods for x-ray diffraction analysis to provide x-ray diffraction patterns of sufficiently high resolution for three-dimensional structure determination of the protein, as well as methods for rational drug design, based on using amino acid sequence data and/or x-ray crystallography data provided on computer readable media, as analyzed on a computer system having suitable computer algorithms; and atomic coordinates are provided yielding structural information on the lipid binding and lipid transport protein family that includes BPI, LBP, CETP and PLTP

Three-dimensional structure of bactericidal/permeability-increasing protein (BPI)

Methods and materials for the treatment of human meningococcemia are provided in which therapeutically effective amounts of BPI protein products are administered.

Therapeutic uses of bpi protein products for human meningococcemia

Antithrombotic materials and methods are provided for the treatment of thrombotic disorders, in which therapeutically effective amounts of BPI protein products are administered.

Antithrombotic materials and methods

The present invention relates generally to anti-fungal peptides derived from or based on Domain III (amino acids 142-169) of bactericidal/permeability-increasing protein (BPI) and in vivo or in vitro uses of such peptides.

Mitchell B. Fadem

Papers

Anti-fungal peptides