Mohamed F.A. Aly

TL;DR: Area strain seems to adequately identify regional wall motion abnormalities compared with the clinical standard of visual assessment by experienced echocardiographers, and represents a promising novel automatic index that may provide an accurate and reproducible alternative for quantitative assessment of global and regional LV function.

TL;DR: Although 3DSTE-derived LV volumes are underestimated in most patients compared with MRI, measurement of the LVEF revealed excellent accuracy, which reflects various inter-technique differences that preclude direct comparability of their measurements.

TL;DR: Good intra-observer, inter-ob server, and test-retest reliability support the use of three-dimensional STE for routine evaluation of LV volumes and EF, and global and segmental strain measurements also demonstrate high reliability.

TL;DR: 3DE direct volumetric and speckle-tracking methods give comparable and reproducible quantification of LV and LA volumes and function, making interchangeable application a viable option in daily clinical practice.

TL;DR: 3DE is a feasible and reliable tool for assessment of LV dyssynchrony and may have additional value to current selection criteria for accurate prediction of response to CRT.