I read this book the same weekend that the Packers took on the Rams, and the experience of the latter event, obviously, colored my judgment. Although I abhor anything that smacks of being a handbook (like, \"How to Earn a Merit Badge in Neurosurgery\") because too many volumes in biomedical science already evince a boyscout-like approach, I must confess that parts of this volume are fast, scholarly, and significant, with certain reservations. I like parts of this well-illustrated book because Dr. Sj6strand, without so stating, develops certain subjects on technique in relation to the acquisition of judgment and sophistication. And this is important! So, given that the author (like all of us) is somewhat deficient in some areas, and biased in others, the book is still valuable if the uninitiated reader swallows it in a general fashion, realizing full well that what will be required from the reader is a modulation to fit his vision, propreception, adaptation and response, and the kind of problem he is undertaking. A major deficiency of this book is revealed by comparison of its use of physics and of chemistry to provide understanding and background for the application of high resolution electron microscopy to problems in biology. Since the volume is keyed to high resolution electron microscopy, which is a sophisticated form of structural analysis, but really morphology in a modern guise, the physical and mechanical background of The instrument and its ancillary tools are simply and well presented. The potential use of chemical or cytochemical information as it relates to biological fine structure , however, is quite deficient. I wonder when even sophisticated morphol-ogists will consider fixation a reaction and not a technique; only then will the fundamentals become self-evident and predictable and this sine qua flon will become less mystical. Staining reactions (the most inadequate chapter) ought to be something more than a technique to selectively enhance contrast of morphological elements; it ought to give the structural addresses of some of the chemical residents of cell components. Is it pertinent that auto-radiography gets singled out for more complete coverage than other significant aspects of cytochemistry by a high resolution microscopist, when it has a built-in minimal error of 1,000 A in standard practice? I don't mean to blind-side (in strict football terminology) Dr. Sj6strand's efforts for what is \"routinely used in our laboratory\"; what is done is usually well done. It's just that …

Methods in Enzymology.

The Pharmacological Basis of Therapeutics A Textbook of Pharmacology, Toxicology and Therapeutics for Physicians and Medical Students. By Prof. Louis Goodman and Prof. Alfred Gilman. Pp. xiii + 1383. (New York: The Macmillan Company, 1941.) 50s. net.

The Pharmacological Basis of Therapeutics

NMR spectroscopy in the structural elucidation of oligosaccharides and glycosides.

Phytosterols, phytostanols, and their conjugates in foods: structural diversity, quantitative analysis, and health-promoting uses

Overproduction of oxidants (reactive oxygen species and reactive nitrogen species) in the human body is responsible for the pathogenesis of some diseases. The scavenging of these oxidants is thought to be an effective measure to depress the level of oxidative stress of organisms. It has been reported that intake of vegetables and fruits is inversely associated with the risk of many chronic diseases, and antioxidant phytochemicals in vegetables and fruits are considered to be responsible for these health benefits. Antioxidant phytochemicals can be found in many foods and medicinal plants, and play an important role in the prevention and treatment of chronic diseases caused by oxidative stress. They often possess strong antioxidant and free radical scavenging abilities, as well as anti-inflammatory action, which are also the basis of other bioactivities and health benefits, such as anticancer, anti-aging, and protective action for cardiovascular diseases, diabetes mellitus, obesity and neurodegenerative diseases. This review summarizes recent progress on the health benefits of antioxidant phytochemicals, and discusses their potential mechanisms in the prevention and treatment of chronic diseases.

/pdf/antioxidant-phytochemicals-for-the-prevention-and-treatment-373el6axrc.pdf

Antioxidant Phytochemicals for the Prevention and Treatment of Chronic Diseases.

Technoeconomic evaluation of insulated building integrated photovoltaic system as a building envelope

BACKGROUND: Medico-ethnobotanical exploration is an important part of drug research, which provides information on the distribution, availability, and natural habitat of medicinal plants. The collection of specimens and photographs during the survey tours acts as the reference materials for the description and characterization of raw drugs and their botanical source to avoid adulteration and substitution. The present study aimed to explore the potential of the medicinal plants of the Almora forest division and their present status in the natural habitat. METHODS: Medico-ethnobotanical exploration was carried out in the Almora forest division of Kumaun Himalayan region in Uttarakhand, India, from July 2018 to February 2019. Almora, Someshwar, Mohan, and Jaurasi ranges of the Almora forest division were explored in different seasons during these surveys. During exploration, herbarium specimens and photographs of medicinal plants, preferably flowering or fruiting twigs, were collected with locality and GPS data. Plants were identified and also referred to the herbarium of the Regional Ayurveda Research Institute, Ranikhet, Uttarakhand, and the published literature. RESULTS: During these surveys, 204 medicinal plant species were documented with their local name and locality(s) with GPS location showing their distribution. Among the 204 identified medicinal plant species of this region, six species are found under the endangered and threatened category. CONCLUSIONS: There is an urgent need for the conservation of medicinal plants and their natural habitat for their perpetual existence. Further, medicinal plants having commercial potential should be cultivated by local inhabitants for their socioeconomic development.

Mohan S. M. Rawat

Papers

Technoeconomic evaluation of insulated building integrated photovoltaic system as a building envelope

Medico-ethnobotanical exploration of Almora forest division, Uttarakhand, India—Need for the conservation of medicinal plants