J. Appl. Cryst.の発刊に際して

Preactivated thiomers as mucoadhesive polymers for drug delivery.

Organic compounds possessing S–S bonds, often called disulfides or more specifically disulfanes, have been widely applied in various fields ranging from biochemistry to different industrially important polymers, used as synthetic intermediates in other fine chemicals such as catenanes, rotaxanes, micelles, and also in areas like peptidomimetics, self-assembled monolayers (SAMs) etc. Such versatile applications have steered the development of several new methods for the preparation of organic disulfides. The present review has attempted to comprehensively summarize recent advances in the process of S–S bond formation, highlighting plausible mechanistic considerations, scope and limitations.

Recent advances in S–S bond formation

Triazolinediones (TADs) are unique reagents in organic synthesis that have also found wide applications in different research disciplines, in spite of their somewhat “exotic” reputation. In this review, we offer two case studies that demonstrate the possibilities of these versatile and reliable synthetic tools, namely, in the field of polymer science as well as in more recently emerging applications in the field of click chemistry. As the general use of triazolinediones has always been hampered by the limited commercial and synthetic availability of such reagents, we also offer a review of the available TAD reagents, together with a detailed discussion of their synthesis and reactivity. This review thus aims to serve as a practical guide for researchers that are interested in exploiting and further developing the exceptional click-like reactivity of triazolinediones in various applications.

https://biblio.ugent.be/publication/8502315/file/8502332.pdf

Triazolinediones as Highly Enabling Synthetic Tools

Alcohols, in particular polyols, are well-known for the synthesis of metal nanoparticles, often acting as reducing agents, solvents, and stabilizers. Given not only their structural flexibility depending on the number of OH functions and their inherent H bonding interactions, but also the wide range of polyol molecular weights readily available, different physicochemical properties (boiling point, polarity, viscosity) could be exploited toward the synthesis of well-defined nanomaterials. In particular, the relevance of the supramolecular structure of polyols has a fundamental impact on the formation of metal nanoparticles, thereby favoring the dispersion of the nanoclusters. In the field of the metal-based nanocatalysis, palladium occupies a privileged position mainly due to its remarkable versatility in terms of reactivity representing a foremost tool in synthesis. In this review, we describe the controlled synthesis of Pd-based nanoparticles in polyol medium, focusing on the progress in terms of tailoring size, morphology, structure, and surface state. Moreover, we discuss the use of palladium nanoparticles, in a polyol solvent, applied in two of the most relevant Pd-catalyzed processes, i.e., couplings and hydrogenation reactions, including multistep processes.

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Palladium Nanoparticles in Polyols: Synthesis, Catalytic Couplings, and Hydrogenations.

Efficient oxidative coupling of thiols and oxidation of sulfides using UHP in the presence of Ni or Cd salen complexes immobilized on MCM-41 mesoporous as novel and recoverable nanocatalysts

Oxo-vanadium(IV) Schiff base complex supported on MCM-41 as an organic–inorganic hybrid heterogeneous catalyst was synthesized with post-grafting of MCM-41 with 3-aminoropropyltrimethoxysilane and subsequent reaction with 3,4-dihydroxybenzaldehyde and then complexation with oxo-vanadium acetylacetonate salt. The catalyst was analysed using a series of characterization techniques such as Fourier transform infrared spectroscopy, small-angle X-ray diffraction, nitrogen absorption isotherm, transmission electron microscopy and thermogravimetric analysis. The data collected provided evidence that the vanadium complex was anchored onto MCM-41. High catalytic activity of this catalyst was observed in the oxidation of various sulfides and thiols (into sulfoxides and disulfides, respectively) with urea hydrogen peroxide as oxidant in high to excellent yields and selectivity under mild conditions. The heterogeneous catalyst could be recovered easily and reused several times without significant loss in catalytic activity and selectivity. Copyright © 2015 John Wiley & Sons, Ltd.

Oxo‐vanadium(IV) Schiff base complex supported on modified MCM‐41: a reusable and efficient catalyst for the oxidation of sulfides and oxidative S–S coupling of thiols

A new Pd‐Schiff‐base complex on boehmite nanoparticles: Its application in Suzuki reaction and synthesis of tetrazoles

A complex moiety containing VO(IV) was anchored covalently into organic-modified Si-MCM-41 to prepare a new catalyst. The prepared materials were characterized using various techniques. Several types of aromatic and aliphatic sulfides were successfully oxidized to the corresponding sulfoxides in good to excellent yields using H2O2 in the presence of a catalytic amount of the catalyst under solvent-free conditions. The results showed that the OH groups of the various compounds such as 2,2-(phenylthio)ethanol and 2-(methylthio)ethanol remained intact under similar conditions. Meanwhile the catalyst was stable in the reaction system, and could be reused at least four times without significant loss of its activity and chemoselectivity. Copyright © 2016 John Wiley & Sons, Ltd.

Immobilization of a vanadium complex onto functionalized nanoporous MCM‐41 and its application as a catalyst for the solvent‐free chemoselective oxidation of sulfide to sulfoxide

A palladium 2-mercapto-N-propylacetamide complex supported on functionalized MCM-41 was prepared by a post-grafting method and considered as an efficient catalyst for CC cross-coupling reactions between various aryl halides and sodium tetraphenylborate, phenylboronic acid, triphenyltin chloride or alkenes. Also, this catalyst shows good reactivity towards amination of aryl halides. This nanocatalyst was characterized using thermogravimetric analysis, X-ray diffraction, scanning electron microscopy, Fourier transform infrared spectroscopy, inductively coupled plasma and transmission electron microscopy techniques. Further results indicated that the heterogeneous catalyst could be recovered easily and reused several times without any loss of its catalytic activity. Copyright © 2016 John Wiley & Sons, Ltd.

Palladium 2‐mercapto‐N‐propylacetamide complex anchored onto MCM‐41 as efficient and reusable nanocatalyst for Suzuki, Stille and Heck reactions and amination of aryl halides

Mohsen Nikoorazm

Papers

Efficient oxidative coupling of thiols and oxidation of sulfides using UHP in the presence of Ni or Cd salen complexes immobilized on MCM-41 mesoporous as novel and recoverable nanocatalysts

Oxo‐vanadium(IV) Schiff base complex supported on modified MCM‐41: a reusable and efficient catalyst for the oxidation of sulfides and oxidative S–S coupling of thiols

A new Pd‐Schiff‐base complex on boehmite nanoparticles: Its application in Suzuki reaction and synthesis of tetrazoles

Immobilization of a vanadium complex onto functionalized nanoporous MCM‐41 and its application as a catalyst for the solvent‐free chemoselective oxidation of sulfide to sulfoxide

Palladium 2‐mercapto‐N‐propylacetamide complex anchored onto MCM‐41 as efficient and reusable nanocatalyst for Suzuki, Stille and Heck reactions and amination of aryl halides