Moom Sinn Aw

TL;DR: Results suggest that polymer-modified implants with a TNT layer are capable of delivering a drug to a bone site over an extended period and with predictable kinetics, and favourable bone cell adhesion suggests that such an implant would have good biocompatibility.

TL;DR: The application of magnetised diatoms as magnetically guided drug delivery microcarriers has been demonstrated in diatom silica microcapsules prepared by purification of diatomaceous earth.

TL;DR: The use of porous silica microshells (microparticles) generated from fossilised diatoms known as diatomite or diatomaceous earth (DE) as a natural drug carrier for drug delivery application is presented in this article.

TL;DR: TNTs are a remarkable material that could potentially revolutionize localized DD therapies, especially in areas of orthopedics and localized chemotherapy, but more extensive ex vivo and in vivo studies should be carried out before TNTs-based DRI could become a feasible technology for real-life clinical applications.

TL;DR: It was found that hydrophilic surfaces of DE microparticles, due to the presence of polar carboxyl, amine or hydrolyzed epoxy group, favor extended release of indomethacin, while the hydrophobic DE surface modified by organic hydrocarbons gives a better sustained release profile for gentamicin.