This paper presents the findings of an empirical study into two organizations' experiences with the adoption and use of CASE tools over time. Using a grounded theory research approach, the study characterizes the organizations' experiences in terms of processes of incremental or radical organizational change. These findings are used to develop a theoretical framework for conceptualizing the organizational issues around the adoption and use of these tools-issues that have been largely missing from contemporary discussions of CASE tools. The paper thus has important implications for research and practice. Specifically, the framework and findings suggest that in order to account for the experiences and outcomes associated with CASE tools, researchers should consider the social context of systems development, the intentions and actions of key players, and the implementation process followed by the organization. Similarly, the paper suggests that practitioners will be better able to manage their organizations' experiences with CASE tools if they understand that such implementations involve a process of organizational change over time and not merely the installation of a new technology.

CASE tools as organizational change: investigating incremental and radical changes in systems development

GATE (Geant4 Application for Emission Tomography) is a Monte Carlo simulation platform developed by the OpenGATE collaboration since 2001 and first publicly released in 2004. Dedicated to the modelling of planar scintigraphy, single photon emission computed tomography (SPECT) and positron emission tomography (PET) acquisitions, this platform is widely used to assist PET and SPECT research. A recent extension of this platform, released by the OpenGATE collaboration as GATE V6, now also enables modelling of x-ray computed tomography and radiation therapy experiments. This paper presents an overview of the main additions and improvements implemented in GATE since the publication of the initial GATE paper (Jan et al 2004 Phys. Med. Biol. 49 4543–61). This includes new models available in GATE to simulate optical and hadronic processes, novelties in modelling tracer, organ or detector motion, new options for speeding up GATE simulations, examples illustrating the use of GATE V6 in radiotherapy applications and 0031-9155/11/040881+21$33.00 © 2011 Institute of Physics and Engineering in Medicine Printed in the UK 881

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GATE V6: a major enhancement of the GATE simulation platform enabling modelling of CT and radiotherapy

Although desalination technologies have been widely adopted as a means to produce freshwater, many of them require large installations and access to advanced infrastructure. Recently, floating structures for solar evaporation have been proposed, employing the concept of interfacial solar heat localization as a high-efficiency approach to desalination. However, the challenge remains to prevent salt accumulation while simultaneously maintaining heat localization. This paper presents an experimental demonstration of a salt-rejecting evaporation structure that can operate continuously under sunlight to generate clean vapor while floating in a saline body of water such as an ocean. The evaporation structure is coupled with a low-cost polymer film condensation cover to produce freshwater at a rate of 2.5 L m−2 day−1, enough to satisfy individual drinking needs. The entire system's material cost is $3 m−2 – over an order of magnitude lower than conventional solar stills, does not require energy infrastructure, and can provide cheap drinking water to water-stressed and disaster-stricken communities.

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A salt-rejecting floating solar still for low-cost desalination

https://www.srs.fs.usda.gov/pubs/ja/ja_lemly017.pdf

Aquatic selenium pollution is a global environmental safety issue.

Top–down control analysis (TDCA) is a useful tool for quantifying constraints on metabolic pathways that might be overcome by biotechnological approaches. Previous studies on lipid accumulation in oilseed rape have suggested that diacylglycerol acyltransferase (DGAT), which catalyses the final step in seed oil biosynthesis, might be an effective target for enhancing seed oil content. Here, increased seed oil content, increased DGAT activity, and reduced substrate:product ratio are demonstrated, as well as reduced flux control by complex lipid assembly, as determined by TDCA in Brassica napus (canola) lines which overexpress the gene encoding type-1 DGAT. Lines overexpressing DGAT1 also exhibited considerably enhanced seed oil content under drought conditions. These results support the use of TDCA in guiding the rational selection of molecular targets for oilseed modification. The most effective lines had a seed oil increase of 14%. Moreover, overexpression of DGAT1 under drought conditions reduced this environmental penalty on seed oil content.

Metabolic control analysis is helpful for informed genetic manipulation of oilseed rape (Brassica napus) to increase seed oil content.

This chapter discusses a current comparator. The design of the various components of a comparator may be affected by these factors. To detect short circuit and insulation faults arising during construction and to confirm the effectiveness of the shielding as it is installed, the probe test should be carried out at frequent intervals during the construction.

Moore Js

Papers

Design and construction