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Morten Bruvold

Researcher at Norwegian University of Science and Technology

Publications -  17
Citations -  2129

Morten Bruvold is an academic researcher from Norwegian University of Science and Technology. The author has contributed to research in topics: Heart failure & Calcium. The author has an hindex of 8, co-authored 17 publications receiving 1951 citations. Previous affiliations of Morten Bruvold include GE Healthcare.

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Intracellular manganese ions provide strong T1 relaxation in rat myocardium.

TL;DR: In this article, the efficacy of manganese ions (Mn2+) as intracellular (ic) contrast agents was assessed in rat myocardium, and the results showed that ic relaxivity induced by Mn2+ ions in ic water was as high as 56 (s mM)(-1), about 8 times and 36 times higher than with Mn 2+ aqua ions and MnDPDP, respectively, in vitro.
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Manganese ions as intracellular contrast agents: proton relaxation and calcium interactions in rat myocardium.

TL;DR: The longitudinal relaxivity of Mn ions in ic water was about one order of magnitude higher than that of MnCl2 in water in vitro [6.9 (s mM)−1], indicating that ic Mn‐protein binding is an important potentiating factor in relaxation enhancement.
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Analyzing equilibrium water exchange between myocardial tissue compartments using dynamical two-dimensional correlation experiments combined with manganese-enhanced relaxography

TL;DR: Tissue T1 value is strongly reduced with increasing enrichment of Mn2+, and eventually a second tissue T1 component emerges, indicating a shift in the equilibrium water exchange between intra‐ and extracellular compartments from the fast‐exchange limit to the slow‐ex exchange regime.