M
Motahare Boozari
Researcher at Mashhad University of Medical Sciences
Publications - 4
Citations - 98
Motahare Boozari is an academic researcher from Mashhad University of Medical Sciences. The author has contributed to research in topics: Flavanone & Sophoraflavanone G. The author has an hindex of 3, co-authored 4 publications receiving 55 citations.
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Impact of curcumin on toll-like receptors.
TL;DR: The available evidence indicates that curcumin inhibits the extracellular TLR 2 and 4 and intracellularTLR9 and thereby exerts a therapeutic effect in diseases such as cancer, inflammation, infection, autoimmune, and ischemic disease.
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Biologically active prenylated flavonoids from the genus Sophora and their structure–activity relationship—A review
TL;DR: Prenylated flavonoids have the potential to be developed as new drugs or supplements for human health, and it is reported that prenylation decreases the plasma absorption but increases the tissue accumulation.
Journal ArticleDOI
Absolute configuration and anti-cancer effect of prenylated flavonoids and flavonostilbenes from Sophora pachycarpa: Possible involvement of Wnt signaling pathway.
Motahare Boozari,Samad Nejad Ebrahimi,Saba Soltani,Zahra Tayarani-Najaran,Seyed Ahmad Emami,Javad Asili,Mehrdad Iranshahi +6 more
TL;DR: Alopecurone J and P showed cytotoxic effect on MCF-7 cell line through Wnt signaling pathway and it seems that the presence of lavandulyl substitution in C-8 position of flavanone structure increased the cytot toxic effect.
Journal ArticleDOI
4,5-Seco-5,10-friedo-abietane-type diterpenoids with anticancer activity from Salvia atropatana Bunge.
Abolfazl Shakeri,Seyedeh Sara Farahmand,Zahra Tayarani-Najaran,Seyed Ahmad Emami,Norbert Kúsz,Judit Hohmann,Motahare Boozari,Fatemeh Zaker Tavallaie,Javad Asili +8 more
TL;DR: In this article, a cytotoxicity-guided isolation of the petroleum ether fraction from the roots of Salvia atropatana for the first time, which has shown to growth inhibition and apoptosis induction in MCF-7 and PC3 cells.