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Murali Jasty

Researcher at Harvard University

Publications -  107
Citations -  11797

Murali Jasty is an academic researcher from Harvard University. The author has contributed to research in topics: Femur & Osteolysis. The author has an hindex of 59, co-authored 107 publications receiving 11520 citations. Previous affiliations of Murali Jasty include VCU Medical Center & Beth Israel Deaconess Medical Center.

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Book ChapterDOI

Periprosthetic Bone Loss in Total Hip Arthroplasty: Polyethylene Wear Debris and the Concept of the Effective Joint Space

TL;DR: The concept of the effective joint space is suggested to include all periprosthetic regions that are accessible to joint fluid and thus accessible to particulate debris to indicate that joint fluid penetrates far more extensively than previously thought.
Journal ArticleDOI

A novel method of cross-linking ultra-high-molecular-weight polyethylene to improve wear, reduce oxidation, and retain mechanical properties: Recipient of the 1999 HAP Paul Award

TL;DR: A novel method of increasing the cross-link density is presented in which UHMWPE is irradiated in air at an elevated temperature with a high-dose-rate electron beam and subsequently is melt-annealed, which leads to the absence of detectable free radicals in the polymer and, as a result, excellent resistance to oxidation of the polymer.
Journal ArticleDOI

The initiation of failure in cemented femoral components of hip arthroplasties

TL;DR: The time relationship in this series suggested that long-term failure of the fixation of cemented femoral components was primarily mechanical, starting with debonding at the interface between the cement and the prosthesis, and continuing as slowly developing fractures in the cement mantle.
Journal ArticleDOI

Production of cytokines around loosened cemented acetabular components. Analysis with immunohistochemical techniques and in situ hybridization.

TL;DR: Investigation of the in vivo features of the chronic inflammatory response to wear particles from orthopaedic joint implants in patients who had had a total hip replacement found that macrophages were the predominant cellular constituents but also that fibroblasts were present and were actively producing collagen.
Journal ArticleDOI

Unified wear model for highly crosslinked ultra-high molecular weight polyethylenes (UHMWPE).

TL;DR: In this article, the authors investigated the wear behavior of three types of cross-linked ultra-high molecular weight polyethylene (UHMWPE) and found that wear resistance increases with crosslink density.