N
N. F. Myasoedov
Researcher at Russian Academy of Sciences
Publications - 288
Citations - 1242
N. F. Myasoedov is an academic researcher from Russian Academy of Sciences. The author has contributed to research in topics: Semax & Tritium. The author has an hindex of 13, co-authored 264 publications receiving 1085 citations.
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Journal ArticleDOI
New development in the tritium labelling of peptides and proteins using solid catalytic isotopic exchange with spillover-tritium
Yu. A. Zolotarev,A. K. Dadayan,Eduard V. Bocharov,Yu. A. Borisov,B. V. Vaskovsky,E. M. Dorokhova,N. F. Myasoedov +6 more
TL;DR: The reaction ability of amino fragments in HSCIE was shown to depend both of their structures and on the availability and the mobility of the peptide chain, which completely retained their biological activity.
Journal ArticleDOI
Natural and hybrid ("chimeric") stable regulatory glyproline peptides.
I. P. Ashmarin,G. E. Samonina,L. A. Lyapina,A. A. Kamenskii,N.G. Levitskaya,N.G. Levitskaya,Igor A. Grivennikov,O. V. Dolotov,L. A. Andreeva,N. F. Myasoedov +9 more
TL;DR: The most interesting approach is the creation of hybrid ("chimeric") peptide drugs combining the unmodified representatives of various natural RPs that distinctly manifest their inherent physiological activities and cooperate with each other in stabilization of whole peptide in vivo.
Journal ArticleDOI
High temperature solid state catalytic isotope exchange with deuterium and tritium
TL;DR: In this paper, a method for synthesizing tritium- or deuterium-labeled amino acids, peptides and biogenic amines through high temperature solid state catalytic isotope exchange (HSCIE) is proposed.
Journal ArticleDOI
Ligand-exchange chromatography of amino acid race-mates on separon gels containing L-proline or L-hydroxyproline groupings
Igor A. Yamskov,Boris B. Berezin,Vadim A. Davankov,Yu. A. Zolotarev,I.N. Dostavalov,N. F. Myasoedov +5 more
TL;DR: Asymmetric resins chelating copper(II) ions to L -proline or L -hydroxyproline ligands fixed in macroporous methacrylate copolymers were synthesized as mentioned in this paper.
Journal ArticleDOI
In vitro and in vivo opioid activity of [DPro6]dermorphin, a new dermorphin analogue
Maria Broccardo,A.B. Usenko,M.G. Uranova,L. S. Guzevatykh,A.A. Kamensky,L. A. Andreeva,L.Y. Alfeeva,N. F. Myasoedov,E. Giannini,Giovanna Improta,T. G. Emel’yanova +10 more
TL;DR: The data overall suggest that structural maneuvering in the Pro(6)-residue of the DM molecule changes its affinity for mu-opioid receptor subtypes and confirms the usefulness of experimental studies involving structural modifications in obtaining new therapeutic agents.