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N. Sitaram
Researcher at National Institutes of Health
Publications - 6
Citations - 697
N. Sitaram is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Sleep induction & Cholinergic. The author has an hindex of 6, co-authored 6 publications receiving 690 citations.
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Journal ArticleDOI
Cholinergic regulation of mood and REM sleep: Potential model and marker of vulnerability to affective disorder
TL;DR: The authors believe that increased cholinergic sensitivity and REM density may be biological markers of increased vulnerability to bipolar affective illness.
Journal ArticleDOI
REM Sleep Induction by Physostigmine Infusion During Sleep
TL;DR: Physostigmine, an anticholinesterase agent that increases acetylcholine at the synapse, in a dose of 0.5 milligram was given intravenously to seven normal human volunteers and induced REM sleep, suggesting that cholinergic mechanisms play a role in the induction of REM sleep and in modulating cortical arousal mechanisms.
Journal ArticleDOI
Faster Cholinergic REM Sleep Induction in Euthymic Patients with Primary Affective Illness
TL;DR: These results, and others, suggest that patients with primary affective illness may have a supersensitive cholinergic system both when they are ill and when their symptoms are in clinical remission.
Journal Article
A twin study of cholinergic REM induction
TL;DR: The present finding of twin concordance in response to arecoline suggests genetic variation in sensitivity of CNS muscarinic cholinergic receptors may play an etiologic role in affective disorder.