The invention provides a method for extracting PPA (PiPerlonguminine), which comprises the following steps: firstly, extracting by using absolute alcohol to obtain alcohol extract; and further carrying out continuous separation by using silica gel columns for two times to obtain pure PPA crystal after crystallization. The method of the invention can remove a large amount of impurities, thus obtaining the PPA with the purity thereof being as high as 85% to 95%; moreover, the method of the invention has the advantages of low cost and high extraction efficiency, dispenses with toxic reagents in short supply and technically complex equipment and facilitates the batch production; and particularly, the PPA obtained by the method of the invention is low in toxicity and high in activity. The invention further provides a drug preparation comprising the PPA, a preparation method thereof and an application thereof in preparing drugs for treating hyperlipidaemia.

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Papers

Method for extracting PiPerlonguminine and drug combination comprising same