https://scholarlypublications.universiteitleiden.nl/access/item%3A2978611/view

Microplastics in freshwater and terrestrial environments: Evaluating the current understanding to identify the knowledge gaps and future research priorities.

Microplastics in freshwater systems: A review of the emerging threats, identification of knowledge gaps and prioritisation of research needs

Microplastics are a pollutant of environmental concern Their presence in food destined for human consumption and in air samples has been reported Thus, microplastic exposure via diet or inhalation could occur, the human health effects of which are unknown The current review article draws upon cross-disciplinary scientific literature to discuss and evaluate the potential human health impacts of microplastics and outlines urgent areas for future research Key literature up to September 2016 relating to accumulation, particle toxicity, and chemical and microbial contaminants was critically examined Although microplastics and human health is an emerging field, complementary existing fields indicate potential particle, chemical and microbial hazards If inhaled or ingested, microplastics may accumulate and exert localized particle toxicity by inducing or enhancing an immune response Chemical toxicity could occur due to the localized leaching of component monomers, endogenous additives, and adsorbed enviro

Plastic and Human Health: A Micro Issue?

Distribution and importance of microplastics in the marine environment: A review of the sources, fate, effects, and potential solutions

http://www.expeditionmed.eu/fr/wp-content/uploads/2015/02/Van-Cauwenberghe-2014-microplastics-in-cultured-shellfish1.pdf

Microplastics in bivalves cultured for human consumption.

In this study, we investigated if industrial high-density polyethylene (HDPE) particles, a model microplastic free of additives, ranging > 0–80 μm are ingested and taken up into the cells and tissue of the blue mussel Mytilus edulis L. The effects of exposure (up to 96 h) and plastic ingestion were observed at the cellular and subcellular level. Microplastic uptake into the gills and digestive gland was analyzed by a new method using polarized light microscopy. Mussel health status was investigated incorporating histological assessment and cytochemical biomarkers of toxic effects and early warning. In addition to being drawn into the gills, HDPE particles were taken up into the stomach and transported into the digestive gland where they accumulated in the lysosomal system after 3 h of exposure. Our results show notable histological changes upon uptake and a strong inflammatory response demonstrated by the formation of granulocytomas after 6 h and lysosomal membrane destabilization, which significantly inc...

Nadia Nadia von Moos

Papers

Uptake and effects of microplastics on cells and tissue of the blue mussel Mytilus edulis L. after an experimental exposure