Neal B. Blatt

TL;DR: The KDIGO criteria describe clinically relevant AKI in a broad pediatric critical care population and showed that AKI was associated with increased odds of ICU mortality and worsening stages of AKI were associated with increase ICU LOS.

TL;DR: It is suggested that weight-based definitions of FO are useful in defining FO at CRRT initiation and are associated with increased mortality in a broad PICU patient population.

TL;DR: Early postoperative fluid overload is associated with suboptimal outcomes in infants following cardiac surgery and may be an important risk factor for adverse outcomes with all degrees of acute kidney injury.

TL;DR: The data demonstrate an association between fluid overload at continuous renal replacement therapy initiation and mortality in pediatric patients receiving extracorporeal membrane oxygenation, and suggest that intervening prior to the development of significant fluid overload may be more clinically effective than attempting fluid removal aftersignificant fluid overload has developed.

TL;DR: This review discusses what is known about apoptotic pathways and its implication for normal cellular function and describes the characteristic morphological changes of apoptosis.