N
Nicola Ehlken
Researcher at University Hospital Heidelberg
Publications - 50
Citations - 2883
Nicola Ehlken is an academic researcher from University Hospital Heidelberg. The author has contributed to research in topics: Pulmonary hypertension & Survival rate. The author has an hindex of 24, co-authored 50 publications receiving 2542 citations. Previous affiliations of Nicola Ehlken include Heidelberg University & University of Salerno.
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Journal ArticleDOI
Exercise and Respiratory Training Improve Exercise Capacity and Quality of Life in Patients With Severe Chronic Pulmonary Hypertension
Derliz Mereles,Nicola Ehlken,Sandra Kreuscher,Stefanie Ghofrani,Marius M. Hoeper,Michael Halank,F. Joachim Meyer,Gabriele Karger,Jan Buss,Jana Juenger,N. Holzapfel,Christian Opitz,Jörg Winkler,Felix F.J. Herth,Heinrike Wilkens,Hugo A. Katus,Horst Olschewski,Ekkehard Grünig +17 more
TL;DR: It is indicated that respiratory and physical training could be a promising adjunct to medical treatment in severe PH and the effects add to the beneficial results of modern medical treatment.
Journal ArticleDOI
Safety and Efficacy of Exercise Training in various forms of Pulmonary Hypertension
Ekkehard Grünig,Mona Lichtblau,Nicola Ehlken,Hossein Ardeschir Ghofrani,Frank Reichenberger,Gerd Staehler,Michael Halank,Christine Fischer,Hans-Jürgen Seyfarth,Hans Klose,Andreas Meyer,Stephan Sorichter,Heinrike Wilkens,Stephan Rosenkranz,Christian Opitz,Hanno Leuchte,Gabriele Karger,Rudolf Speich,Christian Nagel +18 more
TL;DR: Exercise training in PH is an effective but not a completely harmless add-on therapy, even in severely diseased patients, and should be closely monitored.
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Stress Doppler Echocardiography in Relatives of Patients With Idiopathic and Familial Pulmonary Arterial Hypertension Results of a Multicenter European Analysis of Pulmonary Artery Pressure Response to Exercise and Hypoxia
Ekkehard Grünig,Sylvia Weissmann,Nicola Ehlken,Anna Fijałkowska,Christine Fischer,Thierry Fourme,Nazzareno Galiè,Ardeschir Ghofrani,Rachel E. Harrison,Sandrine Huez,Marc Humbert,Bart Janssen,Jarosław Kober,Rolf Koehler,Rajiv D. Machado,Derliz Mereles,Robert Naeije,Horst Olschewski,Steeve Provencher,Frank Reichenberger,Kathleen Retailleau,Guido Rocchi,Gérald Simonneau,Adam Torbicki,Richard C. Trembath,Werner Seeger +25 more
TL;DR: Pulmonary hypertensive response to exercise and hypoxia in idiopathic/familial PAH relatives appears as a genetic trait with familial clustering, being correlated to but not caused by a BMPR2 mutation.
Journal ArticleDOI
Exercise training improves peak oxygen consumption and haemodynamics in patients with severe pulmonary arterial hypertension and inoperable chronic thrombo-embolic pulmonary hypertension: a prospective, randomized, controlled trial
Nicola Ehlken,Mona Lichtblau,Hans Klose,Johannes Weidenhammer,Christine Fischer,Robert Nechwatal,Sören Uiker,Michael Halank,Karen M. Olsson,Werner Seeger,Henning Gall,Stephan Rosenkranz,Heinrike Wilkens,Dirk Mertens,Hans-Jürgen Seyfarth,Christian Opitz,Silvia Ulrich,Benjamin Egenlauf,Ekkehard Grünig +18 more
TL;DR: The improvements of CI at rest and during exercise indicate that exercise training may improve the right ventricular function, and large multicentre trials are necessary to confirm these results.
Journal ArticleDOI
Assessment and Prognostic Relevance of Right Ventricular Contractile Reserve in Patients With Severe Pulmonary Hypertension
Ekkehard Grünig,Henning Tiede,Esi Otuwa Enyimayew,Nicola Ehlken,Hans-Jürgen Seyfarth,Eduardo Bossone,Antonello D'Andrea,Robert Naeije,Horst Olschewski,Silvia Ulrich,Christian Nagel,Michael Halank,Christine Fischer +12 more
TL;DR: Exercise-induced PASP increase is of high clinical and prognostic relevance in pulmonary hypertension patients and may indicate right ventricular contractile reserve, and stress Doppler echocardiography may be a useful tool for prognostic assessment inmonary hypertension patients.