Nieves García-Quintans

TL;DR: It is found that SirT1 regulates the expression of several antioxidant genes in bovine aortic endothelial cells, including Mn superoxide dismutase, catalase, peroxiredoxins 3 and 5, and can be localized in the regulatory regions of these genes.

TL;DR: This acid stress response seems to provide L. lactis biovar diacetylactis with a selective advantage resulting from cometabolism of glucose and citrate at low pHs.

TL;DR: The results support that this biosynthetic pathway is induced at the transcriptional level by acidic growth conditions, presumably contributing to lactococcal pH homeostasis by synthesis of neutral compounds and by decreasing levels of pyruvate.

TL;DR: It was shown that the beneficial effect of citrate on growth under acid stress conditions is not primarily due to the concomitant alkalinization of the medium but stems from less expenditure of ATP, derived from glucose catabolism, to achieve pH homeostasis.

TL;DR: Nieves Garcia Quintans, Victor Blancato, Guillermo Repizo Christian Magni and Paloma Lopez Centro de Investigaciones Biologicas, Consejo Superior de Investigación Cientificas, Ramiro de Maeztu 9, 28040-Madrid, Spain; Instituto de Biologia Molecular and Celular de Rosario and Departamento de Microbiologia, Facultad de Ciencias Bioquimicas and Farmaceuticas, Universidad Nacional deRosario 2000-Rosario