N
Nik Veldhoen
Researcher at University of Victoria
Publications - 68
Citations - 3073
Nik Veldhoen is an academic researcher from University of Victoria. The author has contributed to research in topics: Gene expression & Thyroid. The author has an hindex of 29, co-authored 68 publications receiving 2796 citations. Previous affiliations of Nik Veldhoen include Scripps Research Institute.
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Toxicity of glyphosate-based pesticides to four North American frog species.
TL;DR: Data suggest that surfactant composition must be considered in the evaluation of toxicity of glyphosate-based herbicides, because thyroid hormone receptor beta mRNA transcript levels were elevated by exposure to formulations containing glyphosate and POEA.
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The bactericidal agent triclosan modulates thyroid hormone-associated gene expression and disrupts postembryonic anuran development.
Nik Veldhoen,Rachel C. Skirrow,Heather L. Osachoff,Heidi Wigmore,David J. Clapson,Mark P. Gunderson,Graham van Aggelen,Caren C. Helbing +7 more
TL;DR: Exposure to low levels of triclosan disrupts thyroid hormones-associated gene expression and can alter the rate of thyroid hormone-mediated postembryonic anuran development.
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Exposure to the herbicide acetochlor alters thyroid hormone-dependent gene expression and metamorphosis in Xenopus Laevis.
TL;DR: It is shown that T3-induced metamorphosis of Xenopus laevis, a species commonly used in the laboratory, is accelerated upon acute exposure to an environmentally relevant level of acetochlor.
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PCB-related alteration of thyroid hormones and thyroid hormone receptor gene expression in free-ranging harbor seals (Phoca vitulina).
Maki Tabuchi,Nik Veldhoen,Neil Dangerfield,Steven J. Jeffries,Caren C. Helbing,Peter S. Ross +5 more
TL;DR: These findings suggest that the TH system in harbor seals is highly sensitive to disruption by environmental contaminants, which not only may lead to adverse effects on growth and development but also could have important ramifications for lipid metabolism and energetics in marine mammals.
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Characterization of the histone H2A.Z-1 and H2A.Z-2 isoforms in vertebrates
Deanna Dryhurst,Toyotaka Ishibashi,Toyotaka Ishibashi,Kristie L. Rose,Kristie L. Rose,José M. Eirín-López,Darin McDonald,Begonia Silva-Moreno,Nik Veldhoen,Caren C. Helbing,Michael J. Hendzel,Jeffrey Shabanowitz,Donald F. Hunt,Juan Ausió +13 more
TL;DR: The biochemical, gene expression, and phylogenetic data suggest that the H2A.Z-1 and H2 a.z-2 variants function similarly yet they may have acquired a degree of functional independence during vertebrate evolution.