Ning Chen

TL;DR: Cord blood transfusion into the systemic circulation of G93A mice delayed disease progression at least 2-3 weeks and increased lifespan of diseased mice, indicating that cord blood may have therapeutic potential in this noninvasive cell-based treatment of ALS.

TL;DR: The initial characterization suggests that a subpopulation of cells exists within the HUCB mononuclear fraction that seems to have the potential to become neural cells, which could then be used in the development of cell‐based therapies for brain injuries and diseases.

TL;DR: MCP-1 and MIP-1alpha expression were significantly increased in the ischemic hemisphere of brain, and significantly promoted HUCB cell migration compared to the contralateral side, suggesting that the increased chemokines in theIschemic area can bind cell surface receptors on H UCB, and induce cell infiltration of systemically delivered HUCBs cells into the CNS in vivo.

TL;DR: Recent findings showing the robustness of adult stem cells derived from hUCB and their potential as a source of transplant cells for the treatment of diseased or injured brains and spinal cords are focused on.

TL;DR: It is concluded that gedunin has in vitro activity against ovarian cancer cells and, further, may enhance the antiproliferative effect of cisplatin.