O
Oktay Tacar
Researcher at Victoria University, Australia
Publications - 3
Citations - 1935
Oktay Tacar is an academic researcher from Victoria University, Australia. The author has contributed to research in topics: Doxorubicin & Autophagy. The author has an hindex of 3, co-authored 3 publications receiving 1580 citations.
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Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems
TL;DR: The frontline drug doxorubicin has been used for treating cancer for over 30 years but causes toxicity to most major organs, especially life‐threatening cardiotoxicity, which forces the treatment to become dose‐limiting.
Journal ArticleDOI
Doxorubicin-induced death in tumour cells and cardiomyocytes: is autophagy the key to improving future clinical outcomes?
Oktay Tacar,Crispin R. Dass +1 more
TL;DR: Doxorubicin, a commonly used frontline chemotherapeutic agent for cancer, is not without side‐effects but the original thinking that the drug causes necrosis in tumours has largely given way to its link with apoptosis over the past two decades.
Journal ArticleDOI
Cardiomyocyte apoptosis vs autophagy with prolonged doxorubicin treatment: Comparison with osteosarcoma cells
Oktay Tacar,Sivanjah Indumathy,Mei Lin Tan,Swati Baindur-Hudson,Anna M Friedhuber,Crispin R. Dass +5 more
TL;DR: Whether low‐dose Dox treatment had pro‐autophagic effects in cardiomyocytes as well as osteosarcoma cells is investigated.