Olivia Smith Spicer

TL;DR: Results indicate that a compensatory mechanism is being activated, which is probably primed early on upon Gn rh3 neuron differentiation and possibly confined to Gnrh3 neurons, and potential compensation factors and sensitive windows of time for compensation during development and puberty should be explored.

TL;DR: The results demonstrate the existence of a redundant reproductive regulatory system that comes into play when Gnrh2 and Gnrh3 are lost, including the upregulation of several reproductive and feeding factors, neuronal plasticity of Scg2, and downregulation of Agrp1.

TL;DR: The results suggest that Lpxrfa may act as a reproductive inhibitory neuropeptide in the zebrafish that interacts with Gnrh3 neurons in the brain and with gonadotropes in the pituitary, while also potentially utilizing the Kiss2/Kiss1ra pathway.

TL;DR: A role for Gnrh2 in controlling satiation in zebrafish along with a minor role in maintaining optimal oocyte quality in females is suggested, suggesting a role of this peptide in metabolism regulation along with the canonical role in regulating reproduction.

TL;DR: In this paper , the authors examined human caudate nucleus tissue samples for the expression of transient receptor potential cation channel subfamily V member 4 (TRPV4) and amyloid precursor protein (APP).