This invention includes a wettable biomedical device containing a high molecular weight hydrophilic polymer and a hydroxyl-functionalized silicone-containing monomer.

Biomedical devices containing internal wetting agents

A soft contact lens containing a silicone-hydrogel made by curing a reaction mixture containing a silicone-containing monomer.

Soft contact lenses

A process for preparing silicone hydrogel contact lenses where machining operations are employed to produce a lens having a desired final shape comprises: providing a monomeric mixture comprising a silicone-containing monomer, a hydrophilic monomer and an organic diluent; charging the mixture to a mold and curing the formulation in the mold to obtain a shaped article; removing organic diluent from the shaped article to improve machineability of the article; and machining the shaped article to obtain a contact lens having a desired configuration.

Process for making silicone containing hydrogel lenses

A silicone hydrogel polymer prepared by curing a reaction mixture comprising a hydroxyalkylamine-functional silicone-containing monomer.

Silicone hydrogel polymers

A method for forming shaped hydrogel articles such as soft contact lenses wherein hydrophilic monomers are mixed with an inert diluent prior to polymerization, and the diluent is replaced with water following the polymerization. Diluents yielding optically clear hydrogels with good mechanical properties are selected on the basis of their viscosity and their Hanson cohesion parameters relative to the cohesion parameters of the polymeric component of the hydrogel.

Method of forming shaped hydrogel articles

A CORNEAL CONTACT LENS IS MADE BY POLYMERIZING A CATALYZED MIXTURE OF ACRYLATES AND/OR METHACRYLATES OF POLYHYDRIC ALCOHOLS WITH A WATER MISCIBLE SOLVENT IN A MOLD CAVITY HAVING A SPHERICALLY CONCAVE BOTTOM SURFACE AND BEING ROTATED ABOUT AN AXIS PERPENDICUAR TO THAT SURFACE AT A SPEED TO PRODUCE AN EXPOSED CONCAVE SURFACE OF THE POLYMERIZATION MIXTURE, WHICH IS SUFFICIENTLY DIFFERENT FROM A PARABOLOID SHAPE BECAUSE OF SURFACE TENSION EFFECTS TO HAVE A CENTER EFFECTIVE AS A CORRECTIVE LENS.

Otto Wichterle

Papers

Method of centrifugally casting thin edged corneal contact lenses

Verfahren zur Herstellung von Kontaktlinsen oder Kontaktschalen

Verfahren zur Herstellung von Kontaktlinsen