Ceramic carbon composite electrodes, prepared by incorporating ceramic powders with carbon paste matrices, are shown to facilitate the oxidation of thiol compounds. These electrooxidation processes are applied for the detection of cysteine and thioglycolic acid in hair-treatment products.

Determination of thioglycolic acid and cysteine in hair-treatment products at ceramic carbon composite electrodes

This safety assessment includes Ammonium and Glyceryl Thioglycolate and Thioglycolic Acid Butyl, Calcium, Ethanolamine, Ethyl, Isooctyl, Isopropyl, Magnesium, Methyl, Potassium, and Sodium Thioglycolate, as used in cosmetics. Thioglycolates penetrate skin and distribute to the kidneys, lungs, small intestine, and spleen; excretion is primarily in urine. Thioglycolates were slightly toxic in rat acute oral toxicity studies. Thioglycolates are minimal to severe ocular irritants. Thioglycolates can be skin irritants in animal and in vitro tests, and can be sensitizers. A no-observable-adverse-effect level for reproductive and developmental toxicity of 100 mg/kg per day was determined using rats. Thioglycolates were not mutagenic, and there was no evidence of carcinogenicity. Thioglycolates were skin irritants in some clinical tests. Clinically significant adverse reactions to these ingredients used in depilatories are not commonly seen, suggesting current products are formulated to be practically nonirritating under conditions of recommended use. Formulators should take steps necessary to assure that current practices are followed.

https://journals.sagepub.com/doi/pdf/10.1177/1091581809339890

Final Amended Report on the Safety Assessment of Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Ethyl Thioglycolate, Glyceryl Thioglycolate, Isooctyl Thioglycolate, Isopropyl Thioglycolate, Magnesium Thioglycolate, Methyl Thioglycolate, Potassium Thioglycolate, Sodium Thioglycolate, and Thioglycolic Acid

The article contains sections titled: 

1	Introduction	
2	Physical Properties	
3	Chemical Properties	
4	Production	
5	Analysis	
6	Transportation and Storage	
7	Toxicology	
8	Uses

Mercaptoacetic Acid and Derivatives

Badanie i ocena jakości depilatorów

Identification of mercaptoacetic acid in hair waving and depilatory products containing other mercapto acids is possible by using thin-layer chromatography.However, gas-chromatographic methods are to be preferred for accurate quantitative determination. Four gas-chromatographic methods are proposed; the first and the second involve derivatisation of the mercaptoacetic acid with diazomethane to the methyl ester, methyl thioether derivative. In the third method, the mercaptoacetic acid is converted into its methyl ester by use of p-toluenesulphonic acid. The last method involves the direct chromatography of underivatised mercaptoacetic acid.

P. Bore

Papers

Determination of mercaptoacetic acid in hair waving and depilatory products