P
P. Di Lucia
Researcher at Hoffmann-La Roche
Publications - 2
Citations - 665
P. Di Lucia is an academic researcher from Hoffmann-La Roche. The author has contributed to research in topics: Downregulation and upregulation & Retinoid X receptor. The author has an hindex of 2, co-authored 2 publications receiving 650 citations.
Papers
More filters
Journal ArticleDOI
Inhibition of IL-12 production by 1,25-dihydroxyvitamin D3. Involvement of NF-kappaB downregulation in transcriptional repression of the p40 gene.
Daniele D’Ambrosio,Marco Cippitelli,M G Cocciolo,D. Mazzeo,P. Di Lucia,Rosmarie Lang,Francesco Sinigaglia,Paola Panina-Bordignon +7 more
TL;DR: 1,25(OH)2D3 may negatively regulate IL-12 production by downregulation of NF-kappaB activation and binding to the p40- kappaB sequence, providing a novel interpretation to its immunosuppressive properties.