P
P. Knott
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 32
Citations - 1453
P. Knott is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Homovanillic acid & Dopaminergic. The author has an hindex of 15, co-authored 32 publications receiving 1410 citations. Previous affiliations of P. Knott include York University & Veterans Health Administration.
Papers
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Journal ArticleDOI
Neurochemical correlates of dementia severity in Alzheimer's disease: relative importance of the cholinergic deficits.
Linda M. Bierer,Vahram Haroutunian,S. Gabriel,P. Knott,Lorna S. Carlin,Dushyant P. Purohit,Daniel P. Perl,James Schmeidler,Philip D. Kanof,Kenneth L. Davis +9 more
TL;DR: It is suggested that of all the neurochemical species quantified, the cholinergic indices may be unique in their association with dementia severity, and none of the amines, their metabolites, or the neuropeptides quantified related significantly to dementia severity in the AD cohort.
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Blinded, multi-center validation of EEG and rating scales in identifying ADHD within a clinical sample
Steven M. Snyder,Humberto Quintana,Sandra B. Sexson,P. Knott,A. F M Haque,Donald A. Reynolds +5 more
TL;DR: In this paper, EEG (theta/beta ratio) and ratings scales (Conners rating scales-Revised and ADHD Rating Scales-IV) were collected separately in a blinded protocol.
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Direct evidence of acute, massive striatal dopamine release in gerbils with unilateral strokes.
T. Brannan,Jesse Weinberger,P. Knott,I Taff,Horacio Kaufmann,Daniel M. Togasaki,J Nieves-Rosa,H Maker +7 more
TL;DR: This study is the first direct demonstration of the marked, continuous dopamine release that occurs during acute cerebral ischemia in Mongolian gerbils that suffered a stroke after acute unilateral carotid artery ligations.
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CSF homovanillic acid in schizotypal personality disorder.
Larry J. Siever,Farooq Amin,Emil F. Coccaro,Robert L. Trestman,Jeremy M. Silverman,Thomas B. Horvath,Theresa Mahon,P. Knott,Larry D. Altstiel,Michael H. Davidson +9 more
TL;DR: A central dopaminergic dysfunction associated with the psychotic-like symptoms of schizotypal personality disorder is suggested.
Journal ArticleDOI
Effects of neuroleptic treatment on symptoms of schizophrenia and plasma homovanillic acid concentrations.
Michael Davidson,René S. Kahn,P. Knott,Ramy Kaminsky,Mark E. Cooper,Kimberly DuMont,Seth Apter,Kenneth L. Davis +7 more
TL;DR: There may be a qualitative distinction between responders and nonresponders to dopamine antagonists in schizophrenic patients who improve with administration of neuroleptic drugs but not in patients who fail to display a treatment response.