P
Paolo Fanti
Researcher at University of Texas Health Science Center at San Antonio
Publications - 62
Citations - 3442
Paolo Fanti is an academic researcher from University of Texas Health Science Center at San Antonio. The author has contributed to research in topics: Parathyroid hormone & Bone disease. The author has an hindex of 29, co-authored 58 publications receiving 3144 citations. Previous affiliations of Paolo Fanti include University of Oklahoma & University of Texas at Austin.
Papers
More filters
Journal ArticleDOI
The role of oxidative stress in the pathogenesis of type 2 diabetes mellitus micro- and macrovascular complications: avenues for a mechanistic-based therapeutic approach.
Franco Folli,Domenico Corradi,Paolo Fanti,Alberto M. Davalli,Ana Maria Paez,Andrea Giaccari,Carla Perego,Giovanna Muscogiuri +7 more
TL;DR: The purpose of this review is to examine the mechanisms that link oxidative stress to micro- and macrovascular complications in subjects with type 2 diabetes and to consider the therapeutic opportunities that are presented by currently used therapeutic agents which possess antioxidant properties as well as new potential antioxidant substances.
Journal ArticleDOI
The phytoestrogen genistein reduces bone loss in short-term ovariectomized rats.
Paolo Fanti,Marie-Claude Monier-Faugere,Zhaopo Geng,J. Schmidt,Peter E. Morris,Donald A. Cohen,Hartmut H. Malluche +6 more
TL;DR: This study shows that GEN reduces both trabecular and compact bone loss after ovariectomy and that this protective effect differs from that of estrogen, since it depends on stimulation of bone formation rather than on suppression of bone resorption.
Journal ArticleDOI
Analysis of GSH and GSSG after derivatization with N -ethylmaleimide
TL;DR: This procedure can assay GSH and GSSG in blood and other tissues in 30 min or less and can be prevented by derivatizing GSH with the alkylating agent N-ethylmaleimide (NEM) to form GS-NEM before acid deproteination.
Journal ArticleDOI
In Vitro and In Vivo Effects of Genistein on Murine Alveolar Macrophage TNFα Production
Peter E. Morris,Laura E. Olmstead,April E. Howard-Carroll,George R. Dickens,Michele Goltz,Carrie Courtney-Shapiro,Paolo Fanti +6 more
TL;DR: In vitro incubation with genistein completely inhibited LPS-induced TNFα production by alveolar macrophages (AM) from BALB/c mice and was associated with a decrease in BAL WBC count post-LPS.
Journal ArticleDOI
Targeting NADPH oxidase with a novel dual Nox1/Nox4 inhibitor attenuates renal pathology in type 1 diabetes
Yves Gorin,Rita de Cássia Cavaglieri,Khaled Khazim,Doug Yoon Lee,Francesca Bruno,Sachin Thakur,Paolo Fanti,Cedric Szyndralewiez,Jeffrey L. Barnes,Karen Block,Hanna E. Abboud +10 more
TL;DR: The data indicate that pharmacological inhibition of Nox1/4 affords broad renoprotection in mice with preexisting diabetes and established kidney disease and identifies GKT137831 as a promising compound for the treatment of DN in type 1 diabetes.