Park Choon Sik

TL;DR: In this article, an SNP marker of WDR21A gene for predicting steroidal reactivity of a patient with asthma is selected within a gene WD repeat domain 21A of sequence number 1 and is a polynotide having 8-100 serial DNA sequence with -10073th base(C or G) from a translation initiation point or complementary polynucleotide thereof.

TL;DR: In this paper, a polynucleotide is provided to influence the translation efficiency of a CD40 gene and cause an atopic asthma patient to synthesize IgE excessively by comprising a sequence variant where a CD 40 SNP is located at 5'-UTR, thereby being used as a diagnosis biomarker for predicting the IgE excessive synthesis possibility from a genetic atopic patient.

TL;DR: A biomarker for diagnosing airway hypersensitivity reaction in asthma using single nucleotide polymorphism of PPARGC1B gene is provided to diagnose the severity of asthma.

TL;DR: A gamma secretase inhibitor for treating the respiratory inflammation disease by immunotherapy is provided to reduce the Th2 immunity, to increase the Th1 immunity and to inhibit the notch signal in the respiratory inflammatory disease.

TL;DR: Kim et al. as discussed by the authors found that single nucleotide polymorphism (SNP) of allantoicase (ALLC) in a Korean asthma sufferer can be a genetically predictable factor for predicting treatment response for ICS, especially for the variation of FEV1.