A liquid suspending vehicle comprising arrowroot and xanthan gum, wherein the total solids content is less than 4% w/v. Also disclosed in a method for forming said liquid suspending vehicle comprising adding arrowroot starch and xanthan gum to water; heating the mixture; cooling the mixture e.g. to room temperature; adding a buffer solution and mixing; and adjusting the pH of the formulation as necessary. The arrowroot may be selected from: ‘true’ Indian arrowroot (Maranta arundinacea ), Maranta ramosissima, Maranta allouya, Maranta nobilis, Maranta indica, Tous-les-mois, Tulema arrowroot (Canna coccinea), Brazilian arrowroot (Manihot utilissima or Manihot palmate), Portland arrowroot, (Arum macculatum), Potato farina or British arrowroot, Taro (Colocasia esculenta) or Numda, Tahitian arrowroot (Zamia integrifolia), tapioca from cassava (Manihot esculenta), Polynesian arrowroot, pia (Tacca leontopetaloides), Tacca, Otaheite arrowroot from the pia plant (Pia pinnatifida), or Japanese arrowroot (Pueraria lobata). The formulation may additionally comprise a buffer, flavouring, sweetener, and/or preservative. The buffer may be citric acid, sodium citrate, and/or sodium phosphate. The sweetener may be sucralose, sorbitol, stevia, monk fruit sweetener, and/or sucrose. The preservative may be an antimicrobial and/or an antioxidant such as potassium sorbate, sodium benzoate, methylparaben, and/or propylparaben. The formulation may comprise an active ingredient e.g. a medicament such as co-careldopa, sucralfate, spironolactone, clonazepam, solifenacin, diazepam, methyldopa, bisprolol, riboflavin, or calcium carbonate. The formulation may comprise less than 4 % arrowroot, 0.5 % or less xanthan gum, less than 1 % sweetener, and 2-12 % active. The arrowroot content may be greater than the xanthan gum content, and the ratio of arrowroot to xanthan gum may be 13:1, 12:1, or 6:1. The pH of the formulation may be 4-4.5. The formulation may have a flow index of 0.46 and a yield value in the range 10-60 dynes/cm2. The formulation may be stable and not degrade after one or more freeze-thaw cycles.

Patel Yogesh

Papers

Suspending vehicle formulation