Showing papers by "Patrizia Brigidi published in 1983"

Antimicrobial susceptibility of Bifidobacterium.

Abstract: The susceptibility pattern of 459 strains of bifidobacteria, representing 15 species, to 16 antimicrobial agents was determined by the broth dilution method. The majority of the strains derived from human faeces. Penicillin G, erythromycin, clindamycin, vancomycin and bacitracin were the most active compounds; they inhibited 90% of the strains at less than 1.6 μg/ml. All strains were susceptible to chloramphenicol (MIC 90 = 2.0–5.8 μ g/ml) and also to lincomycin (MIC 50 = 0.64–1.5 μ g/ml). Neomyccin, streptomycin and tetracycline presented a great variability in their activity. Most strains were resistant to polymyxin B, nalidixic acid, kanamycin, gentamicin and metronidazole. The only variation in susceptibility which was observed among the different species concerned Bifidobacterium suis , which generally appeared to be more resistant than other species.

Antimicrobial susceptibility of BifidobacteriumSensibilité des bifidobactéries aux antimicrobiens

Abstract: The susceptibility pattern of 459 strains of bifidobacteria, representing 15 species, to 16 antimicrobial agents was determined by the broth dilution method. The majority of the strains derived from human faeces. Penicillin G, erythromycin, clindamycin, vancomycin and bacitracin were the most active compounds; they inhibited 90% of the strains at less than 1.6 μg/ml. All strains were susceptible to chloramphenicol (MIC90 = 2.0–5.8 μg/ml) and also to lincomycin (MIC50 = 0.64–1.5 μg/ml). Neomyccin, streptomycin and tetracycline presented a great variability in their activity. Most strains were resistant to polymyxin B, nalidixic acid, kanamycin, gentamicin and metronidazole. The only variation in susceptibility which was observed among the different species concerned Bifidobacterium suis, which generally appeared to be more resistant than other species.

Synthesis and Antimicrobial Activity of Some 2‐(2‐Nitroethenyl)naphthofuran and ‐benzofuran Derivatives

Abstract: Some 2-(2-nitroethenyl)naphthofuran and 2-(2-nitroethenyl)benzofuran derivatives were synthesized and tested in vitro for antimicrobial activity. Only 2-(2-nitroethenyl)naphtho[2,1-b]furan exhibits appreciable activity against gram-positive and gram-negative bacteria. Synthese und antimikrobielle Wirkung einiger 2-(2-Nitrovinyl)-Naphthofuran- und -Benzofuran-Derivate Einige 2-(2-Nitrovinyl)naphthofuran- und 2-(2-Nitrovinyl)benzofuran-Derivate wurden hergestellt und auf ihre antimikrobielle in vitro-Aktivitat untersucht. Als einzige Verbindung zeigte 2-(2-Nitrovinyl)naphtho[2,l-b]furan eine signifikante Wirksamkeit gegen grampositive und gramnegative Bakterien.