P
Paul Ashton
Publications - 16
Citations - 814
Paul Ashton is an academic researcher. The author has contributed to research in topics: Controlled release & Drug delivery. The author has an hindex of 7, co-authored 16 publications receiving 814 citations.
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Patent
Polymer-based, sustained release drug delivery system
TL;DR: In this article, the authors present a sustained release system that includes a polymer and a pharmaceutically active agent dispersed in the polymer matrix, where the agent is in granular or particulate form, and has a rate of release from the system that is limited primarily by the rate at which the agent dissolves from the granules into the polymer.
Patent
Polymeric gel delivery system for pharmaceuticals
Paul Ashton,Jianbing Chen +1 more
TL;DR: A pharmaceutically effective compound is a biologically tolerated substance that forms a hydrogel upon exposure to bodily fluids, such as the interstitial fluid surrounding or within a joint.
Patent
In situ gelling drug delivery system
TL;DR: In this paper, the authors presented liquid controlled-release drug delivery compositions, which gel upon injection into the body to form, in situ, controlled release drug implants, using a gel-forming polymer that is insoluble in water, a polyethylene glycol solvent in which the polymer is dissolved, and the drug substance to be delivered.
Patent
Porous silicon drug-eluting particles
TL;DR: In this paper, a biodegradable drug-eluting particle is proposed for the delivery of diagnostic or therapeutic agents, which is useful for treating a patient to obtain a desired local or systemic physiological or pharmacological effect comprising administering a sustained release drug delivery particle.
Patent
Bioerodible sustained release drug delivery systems
TL;DR: In this article, sustained release drug delivery systems, medical devices incorporating said systems, and methods of use and manufacture thereof are described, and the inventive systems feature bioerodible drug delivery devices that include biocompatible solid and bio-compatible fluid compositions.